… B7-H4 (VTCN1/B7x/B7S1) as a potential therapeutic target for the treatment of cancer. The
potential clinical significance of B7-H4 is supported by the high levels of B7-H4 … of B7-H4 has …

… In addition, B7-H4 has the other biological functions, such as protection against type 1 …
Therefore, B7-H4 has been identified as a novel marker or a therapeutic target for the treatment of …

… According to its bifunctional role in inflammation cascade and autoimmunity, it is reasonable
to speculate that B7-H3 could act as a promising therapeutic target for autoimmune diseases…

… B7-H4 on multiple arms of the immune response (27). It is unclear how these effects on
innate responses might impact therapeutic targeting of adaptive responses by B7-H4 blockade. …

… that anti–B7-H4 antibody treatment … B7-H4 as a potential therapeutic target because it was
highly expressed in ACC-I, had a strong association with poor prognosis, and is a drug target …

… B7-H4 was not detected in normal ovaries. These findings validated B7-H4 as a potential
therapeutic target and a potential serum biomarker for ovarian cancer, as normal ovarian tissue …

… Although not yet tested in clinical or pre-clinical models, several therapies targeting B7-H4
could have important anti-inhibitory effects in the tumor microenvironment. Anti-…

… The immunological mechanism mediated by T cells is the main therapeutic target in the
treatment of renal cell carcinoma (RCC) with interleukin (IL)‑2 and interferon (IFN)‑α. The aim of …

… This study validates B7-H4 as an ADC target for breast cancers and demonstrates its
possible use in the treatment of B7-H4 positive breast cancers. Recently, a functional anti-B7-H4 …

… PD-1 and its receptor B7-H1 (PD-L1) are successful therapeutic targets in cancer but less
is known about other B7 family members. Here, we determined the expression level of B7-H3 …