[HTML][HTML] B7-H4 expression is correlated with tumor progression and clinical outcome in urothelial cell carcinoma

M Fan, Q Zhuang, Y Chen, T Ding, H Yao… - … journal of clinical and …, 2014 - ncbi.nlm.nih.gov
… from patients with bladder cancer was assessed by … B7-H4 immunohistochemical staining
was predominantly observed on the membrane and in cytoplasm of the urothelial cancer

Antibody targeting of B7-H4 enhances the immune response in urothelial carcinoma

JR Podojil, AP Glaser, D Baker, ET Courtois… - …, 2020 - Taylor & Francis
B7-H4 enrichment in the bladder tumor subtypes that had relatively low expression of PD-1,
PD-L1, and CTLA-4 including luminal, luminal papillary and luminal-infiltrated tumors using …

[HTML][HTML] B7H4 expression in bladder urothelial carcinoma and immune escape mechanisms

WH Liu, YY Chen, SX Zhu, YN Li, YP Xu… - Oncology …, 2014 - spandidos-publications.com
… that B7-H4 was upregulated in bladder urothelial carcinomaB7-H4 may be involved in
the occurrence and development of BCa, and may be important in bladder urothelial carcinoma

[HTML][HTML] Elevated expression of B7 homolog 4 is associated with disease progression in upper urinary tract urothelial carcinoma

T Mizuno, T Kamai, T Tsuzuki, D Nishihara… - Cancer Immunology …, 2022 - Springer
… Expression of the co-inhibitory molecule B7-H4 in cancer cells may be associated with
tumor progression, due to its inhibition of T cell proliferation and cytokine production in the …

Clinical significance of blocking novel immune checkpoint B7-H4 in urothelial carcinoma of bladder as a potential therapeutic target

D Raja, A Singh, S Kurra, B Nayak, S Kaushal… - Medical Oncology, 2024 - Springer
… wherein B7-H4 and PD-L1 were highly expressed in bladder tumor tissue than in normal
bladder tissue. Positive expression of B7-H4+ tumor cells in UCB and other solid tumors have …

[HTML][HTML] … B7-H3 and CD163 in cancer tissues indicates malignant clinicopathological status and poor prognosis of patients with urothelial cell carcinoma of the bladder

Z Xu, L Wang, J Tian, H Man, P Li… - Oncology …, 2018 - spandidos-publications.com
… The criteria for RC were: Muscle-invasive bladder carcinoma, recurrent Ta/T1 stage non-muscle-invasive
bladder carcinoma and carcinoma in situ refractory to transurethral resection …

Clinical Significance of combinatorial blockade of novel immune checkpoint B7-H4 with PD-L1 in Urothelial Carcinoma of Bladder: A rational therapeutic approach

D Raja, A Singh, S Kurra, B Nayak, S Kaushal… - 2022 - researchsquare.com
… checkpoints (B7-H4 and PD-L1) was assessed in circulation. Molecular expression of immune
checkpoints has been studied in tumors and normal tissue. In-vitroblocking of B7H4 alone …

[HTML][HTML] B7-H4 correlates with clinical outcome and immunotherapeutic benefit in muscle-invasive bladder cancer

Z Liu, K Jin, H Zeng, F Shao, Y Chang, Y Wang… - … Journal of Cancer, 2022 - Elsevier
… among non-inflamed tumors. Herein, we attempt to explore the potential of B7-H4 in survival
prediction and therapeutic guidance in muscle-invasive bladder cancer (MIBC) patients. …

B7-H3 expression in upper tract urothelial carcinoma associates with adverse clinicopathological features and poor survival

Y Koyama, T Morikawa, Y Miyama, J Miyakawa… - … -Research and Practice, 2020 - Elsevier
urothelial carcinoma (UTUC) has not yet been reported. The aim of this study was to examine
the clinical significance of tumor B7-… of B7 family molecules (ie, B7-H1, B7-H3, and B7-H4) …

Fine tuning the immune response through B7‐H3 and B7H4

KH Yi, L Chen - Immunological reviews, 2009 - Wiley Online Library
… new developments regarding B7-H3 and B7-H4 molecules. … to regulate B7-H4 expression
on tumor cells, B7-H4 on tumor cells … cells and macrophage B7-H4, but not tumor B7-H4, were …