Mechanisms of calcium channel modulation by β-adrenergic agents and dihydropyridine calcium agonists

RW Tsien, BP Bean, P Hess, JB Lansman… - Journal of molecular and …, 1986 - Elsevier
… l-adrenergic modulation of calcium channels The main conclusion of this paper is that//adrenergic
.enhancement of cardiac calcium channel … availability of calcium channels for opening, …

alpha-adrenergic antagonists as possible calcium channel inhibitors.

D Atlas, M Adler - Proceedings of the National Academy of …, 1981 - National Acad Sciences
… The a-adrenergic effects of D600 and verapamil should be considered when interpreting
data on Ca2' blockage (7) and in clinical use of these agents (1, 17). The classification of a-…

The effects of calcium channel blocking agents on cardiovascular function

RI Low, P Takeda, DT Mason, AN DeMaria - The American Journal of …, 1982 - Elsevier
… direct effect of calcium agents may be neutralized by a reflex increase in beta adrenergic tone
in … with the highest level of reflex beta adrenergic discharge. The net effect of nifedipine on …

Treatment of poisoning caused by β-adrenergic and calcium-channel blockers

G Shepherd - American Journal of Health-System Pharmacy, 2006 - academic.oup.com
calcium channels and reduce calcium entry into cells during phase 2 of an action potential.
CCBs exhibit different selectivity for cardiac versus vascular channels. … safer than agents that …

Adrenergic regulation of calcium channels in the heart

A Papa, J Kushner, SO Marx - Annual review of physiology, 2022 - annualreviews.org
… a calcium channel inhibitor, Rad, thereby releasing inhibition and increasing calcium influx.
adrenergic agonists are transduced to stimulate calcium influx and contractility in the heart. …

Management of β-adrenergic blocker and calcium channel antagonist toxicity

W Kerns II - Emergency medicine clinics of North America, 2007 - Elsevier
… of antidotal use of calcium, glucagon, catecholamines, insulin-… of β-adrenergic blocker (BB)
and calcium channel antagonist (… Large doses of multiple adrenergic agents may be required. …

Antiarrhythmic agents: the modulated receptor mechanism of action of sodium and calcium channel-blocking drugs

LM Hondeghem, BG Katzung - Annual review of pharmacology …, 1984 - annualreviews.org
… symposia have been published dealing with the calcium channel blocking agents (15-26). …
Frequency de pendent block of ncrve conduction by l3-adrenergic blocking agents. Arch. Int…

[HTML][HTML] Discovery and development of calcium channel blockers

T Godfraind - Frontiers in pharmacology, 2017 - frontiersin.org
… In the section entitled from calcium antagonists to calcium channel blockers, it is recalled …
calcium antagonists on the basis of their effect in depolarized arteries contracted by calcium. …

Classification of calcium antagonists

T Godfraind - The American journal of cardiology, 1987 - Elsevier
agents interacting with calcium channels while having another primary site of action. Other
agents modulate calcium … initially reported with clonidine and other adrenergic agents (Fig. Z).‘…

Calcium channel blockers: an update

MJ Eisenberg, A Brox, AN Bestawros - The American journal of medicine, 2004 - Elsevier
… all agents in this class work by blocking calcium channels, each subclass binds at a unique
location 5, 6. Calcium channel … Abrupt vasodilation with reflex adrenergic activation was …