[HTML][HTML] Engineering exosomes for cancer therapy

KE Gilligan, RM Dwyer - International journal of molecular sciences, 2017 - mdpi.com
exosomes, or alternatively, to directly manipulate exosome content … for exosomes as therapeutic
vehicles for cancer treatment. … for exosome manipulation, isolation, and characterisation. …

[HTML][HTML] Challenges and opportunities in exosome research—Perspectives from biology, engineering, and cancer therapy

X Li, AL Corbett, E Taatizadeh, N Tasnim, JP Little… - APL …, 2019 - pubs.aip.org
… biogenesis, their roles in disease progression, and therapeutic applications and … in exosome
isolation and characterization. We aim to consider critical challenges in exosome research …

Targeted cancer therapy using engineered exosome as a natural drug delivery vehicle

H Gomari, M Forouzandeh Moghadam… - … and therapy, 2018 - Taylor & Francis
cancer cell lines. Citation8 In the present study, targeted exosomes were used to deliver DOX
to HER2+ cancer cells… effects of DOX-loaded targeted exosomes in a murine tumor model. …

[HTML][HTML] Engineered exosomes from different sources for cancer-targeted therapy

M Zhang, S Hu, L Liu, P Dang, Y Liu, Z Sun… - … and targeted therapy, 2023 - nature.com
… of engineered exosomes, especially the spatial and temporal properties. Additionally, we
concluded the recent advances in engineered exosomes in the cancer fields… in cancer therapy. …

Engineered neutrophil-derived exosome-like vesicles for targeted cancer therapy

J Zhang, C Ji, H Zhang, H Shi, F Mao, H Qian, W Xu… - Science …, 2022 - science.org
… N-Ex and exosome-like NNVs in cancer therapy. We first … (SPIONs) for targeted cancer
therapy. Furthermore, we prepared … Our study suggests that the engineered SPION-NNVs are …

Genetically engineered artificial exosome-constructed hydrogel for ovarian cancer therapy

Q Li, Q Song, Z Zhao, Y Lin, Y Cheng, N Karin… - ACS nano, 2023 - ACS Publications
exosome-based peritoneal-localized hydrogel to domesticate peritoneal macrophages as
the therapeutic target for realizing potent ovarian cancer therapy, where artificial exosomes

[HTML][HTML] Genetically engineered cell-derived nanoparticles for targeted breast cancer immunotherapy

X Shi, Q Cheng, T Hou, M Han, G Smbatyan, JE Lang… - Molecular therapy, 2020 - cell.com
… 2 (HER2)-expressing breast cancer by engineering exosomes through genetic display of both
… dually targeting T cell CD3 and breast cancer-associated HER2 receptors. By redirecting …

[HTML][HTML] Exosome-based cancer therapy: implication for targeting cancer stem cells

J Wang, Y Zheng, M Zhao - Frontiers in pharmacology, 2017 - frontiersin.org
… drugs and genes for CSC targeting therapy. Here, we will introduce the … of exosome-based
delivery system in cancer therapy, with particular focus on several exosomal engineering

[HTML][HTML] Harnessing normal and engineered mesenchymal stem cells derived exosomes for cancer therapy: opportunity and challenges

M Ahmadi, M Mahmoodi, M Shoaran… - International Journal of …, 2022 - mdpi.com
… display aptitude as new therapeutic choices for cancer treatment. Exosomes, the most important
… The potential of harnessing exosomes from MSCs (MSCs-Exo) in cancer therapy is now …

[HTML][HTML] Exosome as a delivery vehicle for cancer therapy

B Moon, S Chang - Cells, 2022 - mdpi.com
… can be designed by selecting their source cells, or they can be engineered to incorporate
affinity tags; thus, exosomes show promise as effective delivery vehicles for the complex tumor …