Engineered extracellular vesicles for cancer therapy
X Zhang, H Zhang, J Gu, J Zhang, H Shi… - Advanced …, 2021 - Wiley Online Library
… engineered EVs in cancer therapy are discussed by presenting prominent examples, and the
opportunities and challenges for translating engineered … the potential of exosomes and MVs…
opportunities and challenges for translating engineered … the potential of exosomes and MVs…
Safe and targeted sonodynamic cancer therapy using biocompatible exosome-based nanosonosensitizers
TG Nguyen Cao, JH Kang, JY You… - … applied materials & …, 2021 - ACS Publications
… In this study, exosomes, a class of naturally … and cancer-targeted delivery of a sonosensitizer,
indocyanine green (ICG). The exosomes were surface-engineered with an active cancer-…
indocyanine green (ICG). The exosomes were surface-engineered with an active cancer-…
Engineered exosomes for targeted transfer of siRNA to HER2 positive breast cancer cells
… Despite remarkable improvement in the cancer therapy over the last decades, cancer targeting
has still remained a challenge. Different kinds of nanoparticles and chemical compounds …
has still remained a challenge. Different kinds of nanoparticles and chemical compounds …
Designer exosomes for active targeted chemo‐photothermal synergistic tumor therapy
… exosome can provide functional platforms by engineering … achieve individualized precise
cancer therapy in the future. … We incubated the engineered exosomes with AuNRs for 20 h (on …
cancer therapy in the future. … We incubated the engineered exosomes with AuNRs for 20 h (on …
[HTML][HTML] Engineered targeting tLyp-1 exosomes as gene therapy vectors for efficient delivery of siRNA into lung cancer cells
J Bai, J Duan, R Liu, Y Du, Q Luo, Y Cui, Z Su… - Asian Journal of …, 2020 - Elsevier
… targeting tLyp-1 exosome by gene recombinant engineering for delivery of siRNA to cancer
and cancer stem cells. To … offer a promising gene delivery platform for future cancer therapy. …
and cancer stem cells. To … offer a promising gene delivery platform for future cancer therapy. …
[HTML][HTML] Therapeutic potential of CAR-T cell-derived exosomes: a cell-free modality for targeted cancer therapy
XJ Tang, XY Sun, KM Huang, L Zhang, ZS Yang… - Oncotarget, 2015 - ncbi.nlm.nih.gov
… The engineering of CARs into T cells provides T cells with tumor-targeting capabilities and
intensifies their cytotoxic activity through stimulated cell expansion and enhanced cytokine …
intensifies their cytotoxic activity through stimulated cell expansion and enhanced cytokine …
Exosomes and nanoengineering: a match made for precision therapeutics
PHL Tran, D Xiang, TTD Tran, W Yin… - Advanced …, 2020 - Wiley Online Library
… engineered nanovesicles for precision medicine. Here, recent advances in targeted exosomal
delivery systems engineered … been broadly applied in cancer therapies, including aptamer-…
delivery systems engineered … been broadly applied in cancer therapies, including aptamer-…
Engineered exosome for drug delivery: recent development and clinical applications
J Tian, Z Han, D Song, Y Peng, M Xiong… - International Journal …, 2023 - Taylor & Francis
… the current clinical applications and prospects of engineered exosomes, as well as the … in
exosome engineering, including the standardization of exosome preparation and engineering …
exosome engineering, including the standardization of exosome preparation and engineering …
Immune-cell-derived exosomes for cancer therapy
… exosomes in cancer therapy (Figure 1). First, we briefly outlined the antitumor mechanism
of exosomes … (D) Schematic illustration of engineering exosomes endowed with targeted …
of exosomes … (D) Schematic illustration of engineering exosomes endowed with targeted …
Exosomes as drug carriers for cancer therapy
… These cells were engineered to create exosomes that express lysosome-associated
membrane glycoprotein 2b (Lamp2b) on the membrane. The Lamp2b was fused to the tumor-…
membrane glycoprotein 2b (Lamp2b) on the membrane. The Lamp2b was fused to the tumor-…