Partial EMT in head and neck cancer biology: a spectrum instead of a switch

A Pal, TF Barrett, R Paolini, A Parikh, SV Puram - Oncogene, 2021 - nature.com
… Head and neck cancer is no exception, and in this review, we use head and neck as a
case study for how partial-EMT (p-EMT) cell states may play an important role in cancer

Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment

UY Moreno-Nieves, JK Tay… - Proceedings of the …, 2021 - National Acad Sciences
cell differentiation among the different cell states seen in our scRNA-seq data. Relative to the
cNK cells… resulting in the ieILC1 state and another resulting in the NR4A2-expressing NK-2 …

The biology of head and neck cancer stem cells

Z Zhang, M Sant'Ana Filho, JE Noer - Oral oncology, 2012 - Elsevier
… In this review, we discuss the state-of-the-knowledge on the pathobiology of cancer stem …
of epithelial cells and head and neck cancer initiation. EMT and cancer stem cells

[HTML][HTML] Immune landscape of viral-and carcinogen-driven head and neck cancer

AR Cillo, CHL Kürten, T Tabib, Z Qi, S Onkar, T Wang… - Immunity, 2020 - cell.com
… the complex biology underlying the state of the immune system within the tumor
microenvironment of HNSCC. Further insight into immune cell states will help identify features …

Single-cell sequencing and its applications in head and neck cancer

Z Qi, T Barrett, AS Parikh, I Tirosh, SV Puram - Oral oncology, 2019 - Elsevier
… current state of single-cell technology, summarize its applications in HNSCC and other human
cancers, … in how SCS could revolutionize head and neck cancer diagnosis and treatment. …

[HTML][HTML] Single-cell transcriptomic analysis of primary and metastatic tumor ecosystems in head and neck cancer

SV Puram, I Tirosh, AS Parikh, AP Patel, K Yizhak… - Cell, 2017 - cell.com
cells in tumors affect growth, metastasis, and response to therapy. We profiled transcriptomes
of ∼6,000 single cells from 18 head and neck squamous cell … T cell expression states may …

Molecular pathology of head‐and‐neck cancer

MM Kim, JA Califano - International journal of cancer, 2004 - Wiley Online Library
States and 500,000 people worldwide are diagnosed with head-and-neck squamous cell
expression in metastatic cancer cells compared to nonmetastatic cancer cells and a direct …

[HTML][HTML] Focus on head and neck cancer

L Mao, WK Hong, VA Papadimitrakopoulou - Cancer cell, 2004 - cell.com
… In the United States alone, approximately 28,000 men and … progression of epithelial cells
in the head and neck are not fully … Like most epithelial cancers, HNSCC develops through the …

Improving head and neck cancer therapies by immunomodulation of the tumour microenvironment

AT Ruffin, H Li, L Vujanovic, DP Zandberg… - … Reviews Cancer, 2023 - nature.com
cell response in cancer and chronic viral infections is T cell dysfunction, sometimes termed
exhaustion, a cell state … the importance of further interrogating the state of CD8 + TILs in HPV-…

In vivo native cellular fluorescence and histological characteristics of head and neck cancer.

SP Schantz, V Kolli, HE Savage, G Yu, JP Shah… - … Association for Cancer …, 1998 - AACR
… Head and neck cancers from 35 patients were evaluated … maximum head and neck cancers
and normal mucosa analyzed in vivo. a, … disease states are prone to head and neck cancer