State-of-the-art and emerging treatment options in the management of head and neck cancer: news from 2013

N Denaro, EG Russi, V Adamo, MC Merlano - Oncology, 2014 - karger.com
… Head and Neck cancer is a complex disease which arises in … It is the sixth most common site
of cancer for men and the eighth … HPV among squamous cell head and neck cancer tumors: …

Survival impact of increasing time to treatment initiation for patients with head and neck cancer in the United States

CT Murphy, TJ Galloway, EA Handorf… - Journal of Clinical …, 2016 - ascopubs.org
… ) is increasing in the United States for head and neck squamous cell carcinoma (HNSCC).
Rising … the impact of increasing TTI on survival for patients with HNSCC in the United States. …

Molecular margins in head and neck cancer: Current techniques and future directions

KO Stepan, MM Li, SY Kang, SV Puram - Oral oncology, 2020 - Elsevier
… In this review, we summarize the current state of molecular … characterize the current state of
molecular margin analysis, as … sensitivity of detecting residual cancer cells or the presence of …

[HTML][HTML] Single cell analysis in head and neck cancer reveals potential immune evasion mechanisms during early metastasis

HS Quah, EY Cao, L Suteja, CH Li, HS Leong… - Nature …, 2023 - nature.com
… Alignment of CD8+ T lymphocyte populations is driven by existing knowledge on T-cell
developmental states. The fact that we could pool data across different patients increased the …

[HTML][HTML] Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
neck cancers are derived from the mucosal epithelium in the oral cavity, pharynx and larynx
and are known collectively as head and neck squamous cell … a persistent state of activation …

[HTML][HTML] Immuno-oncological biomarkers for squamous cell cancer of the head and neck: current state of the art and future perspectives

SJ De Keukeleire, T Vermassen, E Hilgert, D Creytens… - Cancers, 2021 - mdpi.com
… Squamous cell cancer of the head and neck is a common malignancy with poor prognosis.
… for state-of-the-art knowledge and biomarkers in squamous cell cancer of the head and neck (…

Head and neck cancer stem cells: the side population

MH Tabor, MR Clay, JH Owen, CR Bradford… - The …, 2011 - Wiley Online Library
… This suggests that the identification of the SP in head and neck cancer cell lines and primary
… for culturing head and neck CSCs and maintaining them in an undifferentiated state, which …

Immunology and immunotherapy of head and neck cancer

RL Ferris - Journal of clinical oncology, 2015 - ascopubs.org
cells in the tumor microenvironment, reviewing immunological principles related to head and
neck cancer, including the concept of cancer … resulting in an immunosuppressed state. Also, …

Modeling head and neck cancer stem cell-mediated tumorigenesis

AT Pearson, TL Jackson, JE Nör - Cellular and molecular life sciences, 2016 - Springer
… starting state [109–111]. Markov chains require the restrictive assumption that different cell
states all have equal growth rates [112], which limits their utility in realistically estimating the …

[HTML][HTML] Single-cell transcriptome profiling of the stepwise progression of head and neck cancer

JH Choi, BS Lee, JY Jang, YS Lee, HJ Kim… - Nature …, 2023 - nature.com
… Notably, Tregs in LP exhibited two peaks of pseudo-time distribution, indicating the alteration
of the T cell states in the premalignant lesions. In particular, we observed the prominent …