… the cytochrome c binding site (two molecules of cytochrome c … 57), and both the
mitochondrial-encoded subunit Cox1p and … of electron transfer between cytochrome c and COX …

… Mitochondria contribute to many processes central to cellular … Mitochondrial shape and
positioning in cells is crucial and is … Cytochrome c released from mitochondria is the point of no …

… Mitochondrial cytochrome c (cyt c) has been found to have dual functions in controlling
both cellular energetic metabolism and apoptosis. Through interaction with apoptotic protease …

… Cytochrome c (Cytc) and cytochrome c oxidase (COX) catalyze the terminal reaction of the
mitochondrial … vast majority of cellular energy, which drives all cellular processes. However, …

… cellular/mitochondrial energy status and accompanied by a loss of sensitivity of COX towards
the cellular … levels at the expense of elevated mitochondrial peroxide production (Boyalla et …

… cellular levels of ADP, AMP, GDP and Pi. The levels of these metabolites regulate a large
range of cellular processes, … of cytochrome oxidase potentially regulate these processes. How…

… mitochondrial outer membrane permeabilization may not invariably lead to cell death. This
review deals with the events involved in Cyt c release from mitochondria, … p35 block cellular …

… Mitochondria are unique cellular organelles that possess their own DNA, encoding thirteen
… Mitochondria are the site of the citric acid cycle and utilize the substrates from this process …

… Thus, HCCS affects cellular levels of cyt c, impacting mitochondrial physiology and cell death.
Here, we review the mechanisms of HCCS function and the roles of heme and residues in …

… In both cases, cytochrome c is released into the extracellular space and can be easily …
of severe cellular damage and death. Possibly, along with cytochrome c, other mitochondrial …