… The aim of this study was to determine whether immunostaining of p16 INK4a is useful in …
that p16 INK4a is a useful marker for adenocarcinoma of the cervix uteri and its precursors. …

… evaluated the use of p16 INK4a in cytological or histological specimens from the uterine
cervix. We also estimated the mean proportion of samples that were positive for p16 INK4a in …

… adenocarcinomas of the cervix uteri are well established, the … In this study, we evaluated the
usefulness of p16ink4a (p16), … of glandular lesions of the cervix uteri and may also improve …

… evolution has resulted in loss of p16INK4a expression.Nonetheless, with standardisation of
… , we find p16INK4a a useful ancillary test.In laboratory practice the value of p16INK4a soon …

… found p16INK4a staining useful when assessing atrophic epithelium (stained negative), …
Therefore, we feel that p16INK4a immunostaining may play a useful role in classifying this …

… The slides were then first stained with the primary antibody (p16 ink4a ready to use for 30±1
min at room temperature) and then with the visualization reagent provided with the kit for 30±…

… the usefulness of p16 INK4A overexpression as a surrogate marker for uterine cervix …
We conducted a retrospective study of 87 uterine cervix specimens, including 7 normal tissue …

… marker is of limited clinical use for the diagnostic evaluation of cervical specimens.23-25
Thus, there is still a significant demand for better biomarkers to identify dysplastic or neoplastic …

… of cervical biopsy between the pathologists. The pathologist 4 revised the diagnosis the most
frequently based on the p16INK4a- … In the current study with the additional use of p16INK4a …

… p16 INK4a overexpression could also be used as a marker of progression tendency in early
lesions of the cervix uteri. The … Unfortunately, morphological criteria alone are not useful in …