[HTML][HTML] Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals

M Danielsson, J Halvardson, H Davies… - European Journal of …, 2020 - nature.com
… Mosaic loss of chromosome Y (LOY) refers to chromosome Y … in circulating immune cells
without chromosome Y [18]. … to 100% of cells without a Y chromosome. Recent studies have …

[HTML][HTML] Chromosome Y loss and drivers of clonal hematopoiesis in myelodysplastic syndrome

P Baliakas, LA Forsberg - haematologica, 2021 - ncbi.nlm.nih.gov
… somatic Y chromosome loss and hematologic malignancies. Mosaic loss of chromosome Y
(LOY) refers to chromosome Y … Furthermore, longitudinal results from subjects without known …

The Y chromosome and its impact on health and disease

MA Wilson - Human Molecular Genetics, 2021 - academic.oup.com
Loss of the Y chromosome Loss of the Y chromosome is … more X chromosomes Loss of
X chromosome increases with … Loss of the Y chromosome Loss of the Y chromosome is …

Loss of Y chromosome in blood is associated with major cardiovascular events during follow-up in men after carotid endarterectomy

S Haitjema, D Kofink, J Van Setten… - Circulation …, 2017 - Am Heart Assoc
… in healthy men from the longitudinal Uppsala Longitudinal Study of Adult Men cohort aged
… The mechanism by which the Y chromosome is lost remains elusive. A recent genome-wide …

[HTML][HTML] Mosaic loss of chromosome Y in blood is associated with Alzheimer disease

JP Dumanski, JC Lambert, C Rasi, V Giedraitis… - The American Journal of …, 2016 - cell.com
… Our previous results show that a fundamentally different genetic variant, ie, lifetime-acquired
loss of chromosome Y (LOY) in blood cells, is associated with all-cause mortality and an …

Loss of chromosome Y and its potential applications as biomarker in health and forensic sciences

B Barros, M Morais, AL Teixeira… - Cytogenetic and Genome …, 2020 - karger.com
… Danielsson M, Halvardson J, Davies H, Moghadam BT, Mattisson J, et al: Longitudinal
changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men …

Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer

LA Forsberg, C Rasi, N Malmqvist, H Davies… - Nature …, 2014 - nature.com
… of changes in the proportion of cells with LOY by longitudinal analyses of five ULSAM subjects
with data collected at two time points 6–14 years apart (Fig. 4). Longitudinallongitudinal

[HTML][HTML] Mosaic loss of Y chromosome and the association to mortality in Danish men aged 56–100 years

DM Hozakowska-Roszkowska, J Mengel-From… - Mechanisms of Ageing …, 2024 - Elsevier
Mosaic loss of the Y chromosome (mLOY) is a common somatic mutation in the blood of
elderly men and several studies have found mLOY in blood cells to be associated with an …

Chromosomes in old age: a six year longitudinal study

LF Jarvik, FS Yen, TK Fu, SS Matsuyama - Human Genetics, 1976 - Springer
… Therefore, it does not seem likely that increased intake of drugs accounted for a significant
portion of the increased chromosome loss found in this longitudinal study of elderly women. …

[HTML][HTML] Genomic alterations in patients with somatic loss of the Y chromosome as the sole cytogenetic finding in bone marrow cells

MM Ouseph, RP Hasserjian, P Dal Cin, SB Lovitch… - …, 2021 - ncbi.nlm.nih.gov
Loss of chromosome Y in ≥75% metaphases is associated … of metaphases involved by
loss of chromosome Y (LOY) ; … Loss of chromosome Y in ≥75% metaphases is significantly …