Repeated mild traumatic brain injury: potential mechanisms of damage

B Fehily, M Fitzgerald - Cell transplantation, 2017 - journals.sagepub.com
… mechanisms that accelerate the development of chronic neurodegenerative diseases, the
mechanistic link between repeated mTBI and CTE pathobiology is yet to be elucidated, and …

Neurodegenerative dementias after traumatic brain injury

C LoBue, CM Cullum, N Didehbani… - The Journal of …, 2018 - Am Neuropsych Assoc
… Magnetic resonance imaging evidence of progression of subacute brain atrophy in
moderate to severe traumatic brain injury. Arch Phys Med Rehabil 2008; 89(Suppl):S35–S44Crossref…

The role of mitochondrial transition pore, and its modulation, in traumatic brain injury and delayed neurodegeneration after TBI

AT Mazzeo, A Beat, A Singh, MR Bullock - Experimental neurology, 2009 - Elsevier
… This explains not only the well described axonal and neuronal defects, after acute injury,
but also the delayed chronic neurodegeneration and cognitive decline occurring in later life, …

Cerebral microvascular injury: a potentially treatable endophenotype of traumatic brain injury-induced neurodegeneration

DK Sandsmark, A Bashir, CL Wellington… - Neuron, 2019 - cell.com
… of the cerebral microvasculature, discuss the relationship of vascular injury to chronic
neurodegenerative sequelae of TBI, and highlight opportunities for preclinical and clinical studies …

Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury

NSN Graham, KA Zimmerman, F Moro… - Science translational …, 2021 - science.org
injury in the chronic phase after TBI measured by FA predicts later neurodegeneration
relationship between acute axonal injury and later white matter neurodegeneration. At each voxel …

Disordered APP metabolism and neurovasculature in trauma and aging: combined risks for chronic neurodegenerative disorders

MD Ikonomovic, Z Mi, EE Abrahamson - Ageing research reviews, 2017 - Elsevier
… To discuss concepts and published research relating to disordered APP metabolism in the
framework of traumatic brain injury (TBI) and aging as dual risk factors for development of late-…

Neurodegeneration and inflammation

MH DeLegge, A Smoke - Nutrition in clinical practice, 2008 - Wiley Online Library
… link between neurodegeneration and chronic inflammation. … brain injury. Apoptosis is known
as programmed cell death and often demonstrates histologic features of acute and chronic

Increased risk of aging-related neurodegenerative disease after traumatic brain injury

S Barker, BD Paul, AA Pieper - Biomedicines, 2023 - mdpi.com
… appreciated that TBI and other neurodegenerative diseases share many pathologic
mechanisms, and that several forms of chronic neurodegeneration display mixed and overlapping …

Diet's Impact on Post-Traumatic Brain Injury Depression: Exploring Neurodegeneration, Chronic Blood–Brain Barrier Destruction, and Glutamate Neurotoxicity …

M Boyko, BF Gruenbaum, A Oleshko, I Merzlikin… - Nutrients, 2023 - mdpi.com
Traumatic brain injury (TBI) has a profound impact on cognitive and mental functioning,
leading to lifelong impairment and significantly diminishing the quality of life for affected …

The role of TDP-43 in military-relevant TBI and chronic neurodegeneration

L Heyburn, VSSS Sajja, JB Long - Frontiers in neurology, 2019 - frontiersin.org
… Traumatic brain injury (TBI) is one of the most common types of injuries sustained by
military personnel. Between 2000 and 2017, TBI was reported in more than 380,000 service …