Use of endotypes, phenotypes, and inflammatory markers to guide treatment decisions in chronic rhinosinusitis

AG Staudacher, AT Peters, A Kato… - Annals of Allergy, Asthma & …, 2020 - Elsevier
… With the advent of new treatment options for Chronic Rhinosinusitis (CRS) comes the ability
… In this review, existing biomarkers and potentially new methods that could guide treatment …

Inflammatory endotypes of chronic rhinosinusitis based on cluster analysis of biomarkers

P Tomassen, G Vandeplas, T Van Zele… - Journal of Allergy and …, 2016 - Elsevier
… with high concentrations of those markers. The group of IL-5–negative clusters, 3 clusters
clinically resembled a predominant chronic rhinosinusitis without nasal polyps (CRSsNP) …

Chronic rhinosinusitis: endotypes, biomarkers, and treatment response

J Gurrola II, L Borish - Journal of Allergy and Clinical Immunology, 2017 - Elsevier
… needs to be approached properly as a continuum of inflammatory processes with high and
variable expression of immune and inflammatory markers. Thus, in the case of eosinophilia, …

Mechanisms and biomarkers of inflammatory endotypes in chronic rhinosinusitis without nasal polyps

AI Klingler, WW Stevens, BK Tan, AT Peters… - Journal of Allergy and …, 2021 - Elsevier
… Our aim was to identify mechanisms and biomarkers associated with inflammatory
Furthermore, we have identified biomarkers that can be useful classifying inflammatory endotypes in …

Correlation between inflammatory biomarkers and disease control in chronic rhinosinusitis with nasal polyps

E De Corso, S Baroni, S Settimi… - International forum of …, 2024 - Wiley Online Library
biomarkers of inflammation in nasal secretions: IL-5 as a marker of eosinophilic inflammation8;
… Association of mucosal organisms with patterns of inflammation in chronic rhinosinusitis. …

Correlation of symptoms, clinical signs, and biomarkers of inflammation in postsurgical chronic rhinosinusitis

SD Racette, RC Wijewickrama… - Annals of Otology …, 2017 - journals.sagepub.com
Objective: The study aimed to evaluate symptoms described by patients with chronic rhinosinusitis
with polypoid changes/nasal polyps and their correlation with computed tomography (…

Longitudinal analysis of inflammatory biomarkers during acute rhinosinusitis

TJ Autio, T Koskenkorva, TK Leino… - The …, 2017 - Wiley Online Library
… Age, sex, and smoking status were not associated with any of the inflammatory biomarkers
(… 50 conscripts with ARS and measured various inflammatory biomarkers at 2 to 3 days of …

Biomarkers in the evaluation and management of chronic rhinosinusitis with nasal polyposis

Y Yao, S Xie, C Yang, J Zhang, X Wu, H Sun - European Archives of Oto …, 2017 - Springer
… In recent years, basic research has shed some light on the pathogenesis of CRSwNP and
has contributed to the discovery of various biomarkers from airway inflammation and tissue …

The diagnostic and prognostic role of biomarkers in chronic rhinosinusitis

JJ Seah, M Thong, DY Wang - Diagnostics, 2023 - mdpi.com
Chronic rhinosinusitis (CRS) refers to an inflammatory process of the sinonasal mucosa
that lasts for more than 12 weeks without resolution of symptoms. It represents a global health …

Nasal biomarker profiles in acute and chronic rhinosinusitis

H Riechelmann, T Deutschle, A Rozsasi… - Clinical & …, 2005 - Wiley Online Library
… consequence of mucosal inflammation. It might also explain why the vast majority of biomarkers
in this … In conclusion, numerous mediators are activated in mucosal inflammation. Simple …