Pathophysiologic mechanisms of chronic rhinosinusitis and their roles in emerging disease endotypes
PP Cao, ZC Wang, RP Schleimer, Z Liu - Annals of Allergy, Asthma & …, 2019 - Elsevier
… The purpose of this review is to summarize the current knowledge regarding inflammatory
endotypes of CRS, their probable underlying pathogenic mechanisms, and how mechanisms …
endotypes of CRS, their probable underlying pathogenic mechanisms, and how mechanisms …
[HTML][HTML] Inflammation and endotyping in chronic rhinosinusitis—a paradigm shift
S Ahern, A Cervin - Medicina, 2019 - mdpi.com
… Basic endotyping of inflammatory markers was furthered in this study by the inclusion of co-…
for future endotyping efforts. Previous work by this group includes profiling inflammation in a …
for future endotyping efforts. Previous work by this group includes profiling inflammation in a …
Chronic rhinosinusitis: endotypes, biomarkers, and treatment response
J Gurrola II, L Borish - Journal of Allergy and Clinical Immunology, 2017 - Elsevier
… Theoretically, in the future, it might be possible to make clinically available the means of
defining the inflammatory endotype based on microarray-based studies with detailed analyses …
defining the inflammatory endotype based on microarray-based studies with detailed analyses …
Endotype-driven care pathways in patients with chronic rhinosinusitis
C Bachert, N Zhang, PW Hellings, J Bousquet - Journal of Allergy and …, 2018 - Elsevier
… Chronic rhinosinusitis (CRS) is defined as an inflammatory disease within the paranasal …
be differentiated further into endotypes of CRS based on inflammatory patterns, including …
be differentiated further into endotypes of CRS based on inflammatory patterns, including …
[HTML][HTML] Longitudinal stability of chronic rhinosinusitis endotypes
… findings, the longitudinal stability of CRS endotypes is not yet known. The aim … inflammatory
CRS endotypes over time and to determine the effect of surgical intervention on inflammatory …
CRS endotypes over time and to determine the effect of surgical intervention on inflammatory …
[HTML][HTML] Cytokine patterns and endotypes in acute and chronic rhinosinusitis
K Scheckenbach, M Wagenmann - Current allergy and asthma reports, 2016 - Springer
… similar clinical and inflammatory patterns. Therefore, attempts to define endotypes in addition
to phenotypes of rhinosinusitis are undertaken. Biological endotypes represent subgroups …
to phenotypes of rhinosinusitis are undertaken. Biological endotypes represent subgroups …
Current insight into treatment of chronic rhinosinusitis: phenotypes, endotypes, and implications for targeted therapeutics
N Chapurin, J Wu, AB Labby, RK Chandra… - Journal of Allergy and …, 2022 - Elsevier
… Chronic rhinosinusitis is characterized by persistent locoregional mucosal inflammation of
the paranasal sinuses … biomarkers, phenotypes, and inflammatory endotypes is a major focus …
the paranasal sinuses … biomarkers, phenotypes, and inflammatory endotypes is a major focus …
[HTML][HTML] Recent advances in understanding chronic rhinosinusitis endotypes
EF Succar, JH Turner - F1000Research, 2018 - ncbi.nlm.nih.gov
… Current research exploring immunologic mechanisms, inflammatory endotypes, and molecular
biomarkers has the potential to more effectively delineate distinct and clinically relevant …
biomarkers has the potential to more effectively delineate distinct and clinically relevant …
Endotype-driven precision medicine in chronic rhinosinusitis
H Lou, C Wang, L Zhang - Expert Review of Clinical Immunology, 2019 - Taylor & Francis
… type 2 inflammation is well ahead of that of other endotypes. … the existence of inflammatory
endotypes within CRS based … data, identifying three CRS endotypes (with and without nasal …
endotypes within CRS based … data, identifying three CRS endotypes (with and without nasal …
[HTML][HTML] Inflammatory endotypes of chronic rhinosinusitis in the Korean population: distinct expression of type 3 inflammation
JY Min, JY Kim, CM Sung, ST Kim, HJ Cho… - Allergy, Asthma & …, 2023 - ncbi.nlm.nih.gov
… In this study, the inflammatory endotypes of CRS in the Korean population were derived …
inflammatory markers, unbiased by phenotype data. Patients were clustered by the inflammatory …
inflammatory markers, unbiased by phenotype data. Patients were clustered by the inflammatory …