Chronic rhinosinusitis endotyping: Sharpening the focus on inflammation
DL Hamilos - Journal of Allergy and Clinical Immunology, 2016 - jacionline.org
… Inflammatory endotypes of chronic rhinosinusitis … inflammatory endotype “clusters” and
used a number of validation steps to confirm the optimal number of CRS clusters. The endotypes …
used a number of validation steps to confirm the optimal number of CRS clusters. The endotypes …
Personalized medicine in chronic rhinosinusitis: phenotypes, endotypes, and biomarkers
AM Bauer, JH Turner - Immunology and Allergy Clinics, 2020 - immunology.theclinics.com
… Inflammatory endotyping has only recently been explored for CRS, but early studies have
shown consistent findings and advanced understanding of the disease process. …
shown consistent findings and advanced understanding of the disease process. …
Highlights in the advances of chronic rhinosinusitis
X Xu, S Reitsma, DY Wang, WJ Fokkens - Allergy, 2021 - Wiley Online Library
… Chronic rhinosinusitis (CRS) is a protracted inflammatory … based on visual analogue scale
for rhinosinusitis. This subgroup has … the evolution towards a particular inflammatory endotype. …
for rhinosinusitis. This subgroup has … the evolution towards a particular inflammatory endotype. …
Advances in the knowledge of the underlying airway remodeling mechanisms in chronic rhinosinusitis based on the endotypes: a review
K Lee, J Tai, SH Lee, TH Kim - International journal of molecular sciences, 2021 - mdpi.com
… Chronic rhinosinusitis (CRS) is a chronic inflammatory condition of the nasal and
paranasal sinus mucosa that affects up to 10% of the population worldwide. CRS is the most …
paranasal sinus mucosa that affects up to 10% of the population worldwide. CRS is the most …
Phenotypes of chronic rhinosinusitis
SH Cho, DL Hamilos, DH Han, TM Laidlaw - The Journal of Allergy and …, 2020 - Elsevier
… and endotypes. Recent advances in our understanding of the pathogenetic mechanisms of
CRS endotypes … to define CRS “endotypes” on the basis of patterns of inflammatory cell and …
CRS endotypes … to define CRS “endotypes” on the basis of patterns of inflammatory cell and …
Clinically relevant phenotypes in chronic rhinosinusitis
JW Grayson, M Cavada… - Journal of Otolaryngology …, 2019 - journals.sagepub.com
… as phenotypes and endotypes are being described. There … inflammatory process. Research
continues to shed more light on different endotypes and phenotypes of airway inflammation, …
continues to shed more light on different endotypes and phenotypes of airway inflammation, …
A review of classification schemes for chronic rhinosinusitis with nasal polyposis endotypes
… type 2 inflammatory cascades for patients with chronic rhinosinusitis. The typical chronic
rhinosinusitis patients in North America and Europe follow a type 2 inflammatory response with …
rhinosinusitis patients in North America and Europe follow a type 2 inflammatory response with …
An integrated analysis of inflammatory endotypes and clinical characteristics in chronic rhinosinusitis with nasal polyps
D Hao, Y Wu, P Li, C Li, T Jiang, Q Zhang… - … of inflammation …, 2022 - Taylor & Francis
… Furthermore, the associations between T1, T3 or mixed endotypes … inflammatory endotypes
are associated with specific clinical characteristics. Improved understandings of endotype-…
are associated with specific clinical characteristics. Improved understandings of endotype-…
Identification of clinically relevant chronic rhinosinusitis endotypes using cluster analysis of mucus cytokines
JH Turner, RK Chandra, P Li, K Bonnet… - Journal of Allergy and …, 2018 - jacionline.org
… Collectively, the inflammatory endotypes outlined in this study confirm that CRS is a
heterogeneous inflammatory disease, and suggest that endotypes likely do not adhere to strict T-…
heterogeneous inflammatory disease, and suggest that endotypes likely do not adhere to strict T-…
Endotyping chronic rhinosinusitis with nasal polyps: understanding inflammation beyond phenotypes
CC Chen, KM Buchheit - American Journal of Rhinology & …, 2023 - journals.sagepub.com
… Overall classification of inflammatory endotypes that have been identified in chronic
rhinosinusitis … In this review, we will focus on the current knowledge of inflammatory endotypes in …
rhinosinusitis … In this review, we will focus on the current knowledge of inflammatory endotypes in …