… Chronic rhinosinusitis is an umbrella term for several phenotypes and mechanistically distinct
inflammatory diseases of the … Chronic rhinosinusitis (CRS) is an umbrella term for common …

… The goal of the current study was to identify inflammatory endotypes in patients with CRS
using an unsupervised cluster analysis of olfactory cleft (OC) biomarkers in a phenotype-free …

… inflammation with disease pathogenesis, additional studies have proposed endotyping CRS
into … Through this work, we seek to further define an atopic endotype of CRS disease. These …

… endotypes based on the core of IL-5: non-type 2 inflammation, moderate type 2 inflammation,
and severe type 2 inflammation. … of inflammation, CRS is divided into four main endotypes …

… For the purpose of this report, we refer to inflammatory endotypes that are characterized by
a coherent group of cytokines and T-effector cells such as Th1, Th2, Th17, Th22, etc. We call …

… The previous dogma that NPs can adequately predict the inflammatory endotype can no
longer be accepted. And it is clearly inflammatory endotype that predicts therapeutic …

… Chronic rhinosinusitis (CRS) is a sinonasal inflammatory disease associated with asthma
comorbidity that affects around 10% of the population world-wide.1 CRS is diagnosed based …

… of endotypes of chronic inflammatory diseases is becoming more and more important
because it is apparent that a traditional management approach of “one size fits all” does not …

… The logistic regression (LR) model in predicting inflammatory endotype of CRSwNP showed
the AUC of 83%, which was better than the diagnostic performance of machine learning …

… understand the complex immunologic and inflammatory patterns in clinically heterogeneous
variants of CRS. Our study has presented unique endotypes of disease that correlate with …