Large-scale gene expression profiling reveals distinct type 2 inflammatory patterns in chronic rhinosinusitis subtypes
MA Tyler, CB Russell, DE Smith, JB Rottman… - Journal of Allergy and …, 2017 - jacionline.org
… which take into account eosinophilic inflammation, comorbid asthma, aspirin … endotypes in
this study; however, we evaluated key type 2 inflammatory markers as a means of endotyping …
this study; however, we evaluated key type 2 inflammatory markers as a means of endotyping …
A Decade of Pathogenesis Advances in Non-Type 2 Inflammatory Endotypes in Chronic Rhinosinusitis: 2012–2022
N DongdongZhu - Int Arch Allergy Immunol, 2023 - karger.com
… type 3 endotypes often have clinical manifestations shared by both type 2 and type 3 inflammatory
endotypes. … can exhibit a type 2 inflammatory endotype and a non-type 2 inflammatory …
endotypes. … can exhibit a type 2 inflammatory endotype and a non-type 2 inflammatory …
Endotypes of chronic rhinosinusitis
J Yip, E Monteiro, Y Chan - … opinion in otolaryngology & head and …, 2019 - journals.lww.com
… chronic rhinosinusitis (CRS), endotyping categorizes disease variants based on their underlying
pathophysiologic mechanisms. Defining CRS endotypes … type 2 inflammation was most …
pathophysiologic mechanisms. Defining CRS endotypes … type 2 inflammation was most …
Can patient-reported outcomes and inflammatory markers define endotype 2 in chronic rhinosinusitis without nasal polyps?
M Plath, L Derycke, M Sand, D Van de Vyvere… - Annals of Allergy …, 2023 - Elsevier
… Chronic rhinosinusitis (CRS) is a heterogeneous disease at the clinical phenotype level (…
at the underlying inflammatory endotype level (type 2 vs non-type 2). Whether the endotype is …
at the underlying inflammatory endotype level (type 2 vs non-type 2). Whether the endotype is …
[HTML][HTML] Exploring the impact of inflammatory endotypes on olfactory function and quality of life in chronic rhinosinusitis patients
NN Zucoloto, FS Aguiar, NMD Lopes… - Brazilian Journal of …, 2024 - SciELO Brasil
… associated with endotypes in Brazilian patients with chronic rhinosinusitis. Type 2 CRS
was the most common endotype, and patients with this endotype had more severe disease, …
was the most common endotype, and patients with this endotype had more severe disease, …
Contemporary classification of chronic rhinosinusitis beyond polyps vs no polyps: a review
… Then the inflammatory endotype dominance separates into a type 2 skewed inflammation …
The non–type 2 classification encompasses everything else not yet known about inflammation …
The non–type 2 classification encompasses everything else not yet known about inflammation …
[HTML][HTML] Comparison between signature cytokines of nasal tissues in subtypes of chronic rhinosinusitis
DK Kim, KM Eun, MK Kim, D Cho… - Allergy, asthma & …, 2019 - synapse.koreamed.org
… Purpose: Endotype in chronic rhinosinusitis (CRS) has been established in the last decade.
… various inflammatory mediators according to different nasal tissues in chronic rhinosinusitis …
… various inflammatory mediators according to different nasal tissues in chronic rhinosinusitis …
Clinical assessment of chronic rhinosinusitis
… Chronic rhinosinusitis (CRS) is a common disease that … CRS in terms of the predominant
endotype or inflammatory pattern … the disease endotypes, as characterized by their inflammatory …
endotype or inflammatory pattern … the disease endotypes, as characterized by their inflammatory …
Revisiting Asian chronic rhinosinusitis in the era of type 2 biologics
Y Yao, M Zeng, Z Liu - Clinical & Experimental Allergy, 2022 - Wiley Online Library
… Chronic rhinosinusitis (CRS) is defined as the inflammation of the mucosa of the nose and
paranasal sinuses … current research progress on CRS endotypes among Asian patients and …
paranasal sinuses … current research progress on CRS endotypes among Asian patients and …
[HTML][HTML] Precision medicine in chronic rhinosinusitis with nasal polyps
K Avdeeva, W Fokkens - Current allergy and asthma reports, 2018 - Springer
… Here, we discuss new treatment options based on specific control of the Th2 inflammatory
endotype most common in CRSwNP that have already shown efficacy in randomized …
endotype most common in CRSwNP that have already shown efficacy in randomized …