Endotypes of chronic rhinitis: a cluster analysis study

Y Meng, H Lou, Y Wang, X Wang, F Cao, K Wang… - Allergy, 2019 - Wiley Online Library
Chronic rhinitis (CR) is currently regarded as a syndrome, which presents as … endotypes.
The aim of this study was to identify the CR endotype clusters and investigate the inflammatory

Chronic rhinosinusitis in Asia

Y Zhang, E Gevaert, H Lou, X Wang, L Zhang… - Journal of Allergy and …, 2017 - Elsevier
… on the basis of the inflammatory endotypes, 83 with minimally … 2 inflammation and total
removal of the diseased mucosa from all sinuses (including the frontal and sphenoid sinuses) …

Asthma and chronic rhinosinusitis: how similar are they in pathogenesis and treatment responses?

A Matucci, S Bormioli, F Nencini, F Chiccoli… - International Journal of …, 2021 - mdpi.com
… Both asthma and chronic rhinosinusitis (CRS) can be differentiated into endotypes: those
with type 2 eosinophilic inflammation and those with a non-type 2 inflammation. A correct …

JESREC score and mucosal eosinophilia can predict endotypes of chronic rhinosinusitis with nasal polyps

T Nakayama, N Sugimoto, N Okada, T Tsurumoto… - Auris Nasus …, 2019 - Elsevier
inflammatory patterns, and unsupervised statistical analyses supported the classification that
can predict endotypes. … mucosal eosinophil count was useful for predicting CRS endotypes. …

Novel findings in immunopathophysiology of chronic rhinosinusitis and their role in a model of precision medicine

X Xu, YK Ong, DY Wang - Allergy, 2020 - Wiley Online Library
… of the pathophysiology of chronic rhinosinusitis (CRS) is … according to the individual's nasal
inflammatory profile. This is usually … at type 2 inflammatory endotypes, perhaps reflecting its …

Advances in chronic rhinosinusitis in 2020 and 2021

Z Xu, Y Huang, T Delemarre, C Cavaliere… - Journal of Allergy and …, 2022 - Elsevier
… This review highlights advances in chronic rhinosinusitis (… differentiators for phenotypes and
endotypes, on recently … need to recognize an inflammatory endotype underlying some forms …

Olfaction: sensitive indicator of inflammatory burden in chronic rhinosinusitis

X Yan, KL Whitcroft, T Hummel - Laryngoscope investigative …, 2020 - Wiley Online Library
endotype and phenotype of CRS. CRSwNP is known as a type 2 reaction, while CRSsNP is
linked with predominantly Th-1 cell response. Type 2 endotypes … 2 inflammatory endotype. …

Comprehensive evaluation of type 2 endotype and clinical features in patients with chronic rhinosinusitis with nasal polyps in Taiwan: a cross-sectional study

YT Lin, CF Lin, CK Liao, TH Yeh - European Archives of Oto-Rhino …, 2023 - Springer
… In the current study, we chose to characterize the endotypes by measuring protein levels
of inflammatory mediators in tissue homogenates as biomarkers because they can be more …

[HTML][HTML] Diversity of TH cytokine profiles in patients with chronic rhinosinusitis: a multicenter study in Europe, Asia, and Oceania

X Wang, N Zhang, M Bo, G Holtappels, M Zheng… - Journal of Allergy and …, 2016 - Elsevier
inflammation, in European patients, whereas more neutrophilic inflammation and endotypes
… Thus in the present study we aimed to evaluate the endotypes of patients with CRS from 2 …

Current and future treatment options for adult chronic rhinosinusitis: focus on nasal polyposis

C Bachert, L Zhang, P Gevaert - Journal of Allergy and Clinical Immunology, 2015 - Elsevier
… need to base new approaches on endotypes of CRS, which are defined … inflammatory
endotype, recurrence of disease over 5 to 10 years is frequent despite parallel anti-inflammatory