Clinical characteristics and surrogate markers of eosinophilic chronic rhinosinusitis in Southern China

K Zuo, J Guo, F Chen, R Xu, G Xu, J Shi… - European archives of oto …, 2014 - Springer
The surrogate markers for subclassifying eosinophilic chronic rhinosinusitis (ECRS) and non-ECRS
remain elusive. We herein performed a cross-sectional study to assess the clinical …

Biomarkers in the evaluation and management of chronic rhinosinusitis with nasal polyposis

Y Yao, S Xie, C Yang, J Zhang, X Wu, H Sun - European Archives of Oto …, 2017 - Springer
… of chronic rhinosinusitis (CRS) characterized by persistent polypoid inflammation of the …
as a potential surrogate marker for tissue eosinophilic inflammation in CRS and are easy to …

Large-scale gene expression profiling reveals distinct type 2 inflammatory patterns in chronic rhinosinusitis subtypes

MA Tyler, CB Russell, DE Smith, JB Rottman… - Journal of Allergy and …, 2017 - jacionline.org
… key type 2 inflammatory markers as a means of … 2 inflammatory markers in clinical phenotypes
but also found notable variation in expression within a given phenotype. One such marker, …

[HTML][HTML] The current findings in eosinophilic chronic rhinosinusitis

T Tsuda, M Suzuki, Y Kato, M Kidoguchi, T Kumai… - Auris Nasus …, 2024 - Elsevier
Chronic rhinosinusitis (CRS) is a persistent inflammatory disease of the nasal cavity and …
by the presence of infiltrating cells and inflammatory markers in the nasal mucosa. Patients with …

Cytokines in chronic rhinosinusitis. Role in eosinophilia and aspirin-exacerbated respiratory disease

WW Stevens, CJ Ocampo, S Berdnikovs… - American journal of …, 2015 - atsjournals.org
Chronic rhinosinusitis is a highly heterogeneous disease. CRSwNP displays a predominant
type 2 inflammatory … Also, gene expression levels of the inflammatory cell markers CD45 (…

Update on the management of chronic rhinosinusitis

RB Cain, D Lal - Infection and drug resistance, 2013 - Taylor & Francis
Chronic rhinosinusitis (CRS) is a common disorder characterized by mucosal inflammation
… amphotericin B on inflammatory markers in patients with chronic rhinosinusitis: a multicenter …

Chronic rhinosinusitis with and without nasal polyps: what is the difference?

W Huvenne, N van Bruaene, N Zhang… - Current allergy and …, 2009 - Springer
chronic rhinosinusitis and the introduction of appropriate disease markers have recently
facilitated disease classification. Evaluation of inflammatorymarkers of eosinophilic inflammation

Molecular and cellular staging for the severity of chronic rhinosinusitis

SE Kountakis, P Arango, D Bradley, ZK Wade… - The …, 2004 - Wiley Online Library
markers and to acknowledge the importance of these basic science parameters in a severity
classification system for chronic rhinosinusitis (… obstructive/inflammatory rhinosinusitis, the …

Dupilumab reduces local type 2 pro‐inflammatory biomarkers in chronic rhinosinusitis with nasal polyposis

K Jonstam, BN Swanson, LP Mannent, LO Cardell… - Allergy, 2019 - Wiley Online Library
… Here, we report the local effect of dupilumab on total IgE levels and markers of
eosinophilic inflammation in nasal secretions and polyp tissues from patients with CRSwNP. …

Can patient-reported outcomes and inflammatory markers define endotype 2 in chronic rhinosinusitis without nasal polyps?

M Plath, L Derycke, M Sand, D Van de Vyvere… - Annals of Allergy …, 2023 - Elsevier
Chronic rhinosinusitis (CRS) is a heterogeneous disease at the clinical phenotype level (…
nasal polyp [CRSwNP]) and at the underlying inflammatory endotype level (type 2 vs non-type 2…