Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models

H Gali‐Muhtasib, M Ocker, D Kuester… - Journal of cellular …, 2008 - Wiley Online Library
… phase of colon carcinogenesis and results in a pronounced inhibition of tumor growth of
three-… TQ has been shown to upregulate p53 and p21 WAF1 protein expression in human colon

The bacterial genotoxin colibactin promotes colon tumor growth by modifying the tumor microenvironment

G Dalmasso, A Cougnoux, J Delmas… - Gut …, 2014 - Taylor & Francis
… To explore the mechanisms involved in the tumor growth … with an increase in tumor
growth and Ki67-positive cell … resulted in a decrease in tumor growth (unpublished data, Fig…

[HTML][HTML] Possible mechanisms by which pro-and prebiotics influence colon carcinogenesis and tumor growth

BS Reddy - The Journal of nutrition, 1999 - Elsevier
… The results of this study provide evidence for potential colon tumor-… the colon tumor inhibitory
property of lyophilized cultures of B. longum was associated with the inhibition of colonic

Nicotine promotes colon tumor growth and angiogenesis through β-adrenergic activation

HPS Wong, LE Yu, EKY Lam, EKK Tai… - Toxicological …, 2007 - academic.oup.com
… that nicotine promoted colon tumor growth by promoting neovascularization. In other studies,
nicotine treatment was found to stimulate angiogenesis and promote tumor growth of Lewis …

Definition of Prostaglandin E2–EP2 Signals in the Colon Tumor Microenvironment That Amplify Inflammation and Tumor Growth

X Ma, T Aoki, T Tsuruyama, S Narumiya - Cancer research, 2015 - AACR
… in colorectal cancer. However, most studies have focused on PGE 2 actions on colorectal
cancer cell lines, and some on colon tumors … in tumor microenvironment of the colon in whole …

An important role for granulocytes in the thermal regulation of colon tumor growth

JR Ostberg, BR Ertel, JA Lanphere - Immunological investigations, 2005 - Taylor & Francis
… of colon tumor growth in mice. … tumor growth control, our data ( Figure 4 ) suggest that mild
thermal stress might also enhance the activity of the granulocytes once they reach the tumor. …

Colon tumor growth and antivascular treatment in mice: complementary assessment with MR elastography and diffusion-weighted MR imaging

L Jugé, BT Doan, J Seguin, M Albuquerque, B Larrat… - Radiology, 2012 - pubs.rsna.org
… During tumor growth, we could confirm that … tumor growth, we saw increased |G*| that
tended to correlate with increased MVD; while the same trend could be observed for both tumor

Epithelial interleukin-4 receptor expression promotes colon tumor growth

FL Koller, DG Hwang, EA Dozier, B Fingleton - Carcinogenesis, 2010 - academic.oup.com
… cancers including breast, brain and colon had up-regulated IL4R expression ( 20–22 ), we
examined a panel of human and murine colon tumor cell lines for IL4Rα expression at both …

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

JS Sebolt-Leopold, DT Dudley, R Herrera… - Nature medicine, 1999 - nature.com
… through MEK/MAPK can inhibit colon tumor growth in vivo. A clinically important aspect of
the pathology of colon cancer is the ability of these tumors to invade and metastasize. MEK …

Recapitulating the human tumor microenvironment: colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth

M Romero-López, AL Trinh, A Sobrino, MMS Hatch… - Biomaterials, 2017 - Elsevier
… comparing ECM from normal human colon and colon tumor that had metastasized to liver. …
obtained tumor tissue from colon tumors that had metastasized to liver. Primary colon tumor