[HTML][HTML] Synergistic Effect of Huangqin Decoction Combined Treatment With Radix Actinidiae chinensis on DSS and AOM-Induced Colorectal Cancer

J Huang, T Jiang, J Kang, J Xu, Y Dengzhang… - Frontiers in …, 2022 - frontiersin.org
Objective: To demonstrate the effectiveness of Huangqin decoction (Huangqin Tang in … “dampness–heat
theory” in preventing and treating colorectal cancer (CRC) with dampness–heat …

[HTML][HTML] Protective effects of Huangqin Decoction against ulcerative colitis and associated cancer in mice

G Chen, Y Yang, C Hu, X Cheng, Y Xu, X Cai… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… Individuals with ulcerative colitis (UC) are at a high risk for developing colorectal cancer (CRC).
Huangqin Decoction (HQD), a traditional Chinese medicinal formula chronicled in the …

Anti-tumour effect of Huangqin Decoction on colorectal cancer mice through microbial butyrate mediated PI3K/Akt pathway suppression

JJ Zhu, HY Liu, LJ Yang, Z Fang… - Journal of Medical …, 2023 - microbiologyresearch.org
… Effect of Huangqin decoction on regulating intestinal flora in colitis mice characterized as
inhibition of the NOD2-dependent pathway. Pharm Biol 2022; 60:108–118 [View Article] …

Network Pharmacology‐Based Study on the Mechanism of Gegen Qinlian Decoction against Colorectal Cancer

Q Fan, L Guo, J Guan, J Chen, Y Fan… - Evidence‐Based …, 2020 - Wiley Online Library
… The dataset contains 34 samples, including 17 primary colorectal cancer tissue samples
and 17 matched normal tissue samples. The raw data were first preprocessed using the Affy …

[HTML][HTML] Network pharmacology and molecular docking-based analyses to predict the potential mechanism of Huangqin decoction in treating colorectal cancer

YJ Li, DX Tang, HT Yan, B Yang, Z Yang… - World Journal of …, 2023 - ncbi.nlm.nih.gov
… A: All potential targets of Huangqin decoction in the treatment of colorectal cancer (purple
nodes); B: Core targets screened based on CytoNCA (yellow nodes); C: The top 28 targets …

A four-component combination derived from Huang-Qin Decoction significantly enhances anticancer activity of irinotecan

XU Dou-Dou, HOU Xiao-Ying, W Ou, W Di… - Chinese Journal of …, 2021 - Elsevier
… The genes which can be targeted by the constituents in HQD and be associated with colon
cancer were retained. The Compound-Target (CT) network was created and analyzed by …

Huang Qin Decoction inhibits the initiation of experimental colitis associated carcinogenesis by controlling the PAD4 dependent NETs

Z Pan, X Xie, Y Chen, S Pan, Z Wu, C Yang, J Liang… - Phytomedicine, 2022 - Elsevier
… found that the inhibitory effect of HQD on intestinal tumors might be related to the activation of
PAD4 … Huang Qin Decoction could inhibit the deterioration of colitis for intestinal cancers by …

[HTML][HTML] … experimental validation to investigate the anticancer mechanism of Qi-Qin-Hu-Chang formula against colitis-associated colorectal cancer through induction of …

Y Wu, Y Fang, Y Li, R Au, C Cheng, W Li, F Xu… - Journal of …, 2024 - Elsevier
Colorectal cancer (CRC) is a commonly occurring cancer and is the second highest cause of
cancer-… The first decoction was strained and the herbs were decocted again using the same …

[HTML][HTML] An optimal combination of four active components in Huangqin decoction for the synergistic sensitization of irinotecan against colorectal cancer

H Zhou, D Hu, X Zhao, S Qin, Q Nong, Y Tian… - Chinese Medicine, 2024 - Springer
… is a first-line treatment for advanced colorectal cancer (CRC). Four components (baicalin,
baicalein, wogonin, and glycyrrhizic acid) derived from Huangqin Decoction (HQD) have been …

[HTML][HTML] Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action

JF Chen, SW Wu, ZM Shi, B Hu - Chinese Medicine, 2023 - Springer
… compound found in Scutellaria baicalensis Georgi (Huang Qin), which has been proven to
… -8/5-FU) after the intervention of Jiedu Sangen decoction (JSD). HIF-1α silencing showed a …