… A recent nested case-control study in the EPIC cohort studied the association of neopterin,
a biomarker of cellular immune activity, with the risk of colorectal cancer and found evidence …

… Myeloid-derived suppressor cells (MDSCs) can significantly dampen host antitumor
immune function and promote tumor development. Possible mechanisms include enhanced …

… major escape mechanisms to antitumor immune response. The … immune response, but also
to the use of immunotherapy. Although immunotherapy is not yet routinely used in colorectal …

… the magnitude of this immune suppression is similar among different types of oncological
surgery. In this study, we compared the innate immune function of patients undergoing three …

… tumor angiogenesis, tumor invasion and immune suppression, and contribute to an
immune suppressive tumor … MCs in cancer promote angiogenesis and tumor invasion into …

… We present an updated review of the biological background and clinical development of
immune checkpoint inhibitors in colorectal cancer (CRC). Early trial results on PD1 and PD-L1 …

… In our study, we investigated the impact of perioperative blood transfusion on the immune
function and prognosis in hereditary colorectal cancer (HCC) and SCC patients. By comparing …

… mechanisms may contribute to tumorigenesis by impairing anti-tumor immunity. This review
will delineate the role of the immune system in IBD-associated cancer with a particular focus …

… To define differences in tumor microenvironment (TME) immune phenotypes between
right and left colorectal cancers (CRCs) and explore their therapeutic implications. Gene …

… ’s fate and determine, by their complex functional interactions, whether or not the progress
… setting of colorectal cancer and highlights the functional mechanisms of those immune cells …