Pivotal roles of tumor‐draining lymph nodes in the abscopal effects from combined immunotherapy and radiotherapy
Z Liu, Z Yu, D Chen, V Verma, C Yuan… - Cancer …, 2022 - Wiley Online Library
… stimulation of abscopal effects, combination therapy with irradiation and … lymph nodes (TDLN)
are essential for effective antitumor immunity induced by radiotherapy, immunotherapy, or …
are essential for effective antitumor immunity induced by radiotherapy, immunotherapy, or …
Lymph node-targeting nanovaccines for cancer immunotherapy
Q Wang, Z Wang, X Sun, Q Jiang, B Sun, Z He… - Journal of Controlled …, 2022 - Elsevier
… Moreover, the recent trends in nanovaccines-based combination cancer immunotherapy are
provided. Finally, the rationality, advantages and challenges of LNs-targeting nanovaccines …
provided. Finally, the rationality, advantages and challenges of LNs-targeting nanovaccines …
Multimodal stratified imaging of nanovaccines in lymph nodes for improving cancer immunotherapy
… In this review, we summarize the strategies for the spatiotemporal visualization of nanovaccines
in lymph nodes, including whole-body in vivo imaging, intravital organ/cell imaging, and …
in lymph nodes, including whole-body in vivo imaging, intravital organ/cell imaging, and …
Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy
DM Francis, MP Manspeaker, A Schudel… - Science translational …, 2020 - science.org
… accumulation within both the TME and its draining lymph nodes (LNs) or LNs alone,
respectively… Targeted delivery of mAb to tumor-draining lymph nodes (TdLNs) alone was …
respectively… Targeted delivery of mAb to tumor-draining lymph nodes (TdLNs) alone was …
Combination immunotherapy: a road map
PA Ott, FS Hodi, HL Kaufman, JM Wigginton… - … for immunotherapy of …, 2017 - Springer
… IDO is expressed constitutively by tumor cells or by host immune cells such as macrophages
and DCs in the tumor or lymph nodes [42, 43], but can also be induced by inflammatory …
and DCs in the tumor or lymph nodes [42, 43], but can also be induced by inflammatory …
Pivotal Roles of Tumor-Draining Lymph Nodes in the Abscopal Effect from Combined Immunotherapy and Radiotherapy
Z Liu, Z Yu, D Chen, M Wu, J Yu - International Journal of Radiation …, 2022 - redjournal.org
… stimulation of abscopal effects, combination therapy of irradiation and PD-1… lymph nodes
(TDLNs) are essential for effective antitumor immunity induced by radiotherapy, immunotherapy …
(TDLNs) are essential for effective antitumor immunity induced by radiotherapy, immunotherapy …
… : durable complete response after combined immunotherapy following resection of primary tumor in a gallbladder cancer patient with distant metastatic lymph nodes of …
B Yi, Z Zhao, H Dong, L Yuan, Y Wu, Y Xu… - Frontiers in …, 2022 - frontiersin.org
… lymph node were predominant in blood during the combined anti-PD-1 treatment.
Conclusions: Chemo-immunotherapy may provide a potential curative option for the lymph node …
Conclusions: Chemo-immunotherapy may provide a potential curative option for the lymph node …
Case report: A case of rare metastasis of gastric cancer to the axillary lymph node metastasis treated with combination immunotherapy
J Wang, Y Cheng, Y Wang, H Liu, S Wu… - Frontiers in …, 2024 - frontiersin.org
… negative in axillary lymph node and left supraclavicular lymph node, and … Combined with
the medical history, both the left axillary lymph nodes and the left supraclavicular lymph nodes …
the medical history, both the left axillary lymph nodes and the left supraclavicular lymph nodes …
[HTML][HTML] Chemotherapy but not the tumor draining lymph nodes determine the immunotherapy response in secondary tumors
… , we hypothesize that combining chemotherapy with ICBT has … immunotherapies are
administered, we established a mouse tumor model that allows evaluation of the immunotherapeutic …
administered, we established a mouse tumor model that allows evaluation of the immunotherapeutic …
Immunotherapy goes local: the central role of lymph nodes in driving tumor infiltration and efficacy
KM Van Pul, MF Fransen, R Van de Ven… - Frontiers in …, 2021 - frontiersin.org
… TDLN, the so-called sentinel lymph node (SLN), we have … epithelium draining lymph nodes)
as well as lymph node-resident … a compelling argument for combining immune adjuvants, …
as well as lymph node-resident … a compelling argument for combining immune adjuvants, …
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