Cyclodextrins in ophthalmic drug delivery
T Loftssona, T Järvinen - Advanced drug delivery reviews, 1999 - Elsevier
… of ophthalmic drugs, and to decrease drug irritation. However, … of cyclodextrins and
administration of cyclodextrins via other … CDs enhance drug delivery through the ocular barrier and …
administration of cyclodextrins via other … CDs enhance drug delivery through the ocular barrier and …
Cyclodextrins in ocular drug delivery: theoretical basis with dexamethasone as a sample drug
T Loftsson, E Stefánsson - Journal of drug delivery science and technology, 2007 - Elsevier
… not readily permeate lipophilic membranes, excess amounts of cyclodextrin will hamper drug
penetration into the eye. Cyclodextrins frequently reduce drug delivery of hydrophilic drugs. …
penetration into the eye. Cyclodextrins frequently reduce drug delivery of hydrophilic drugs. …
Cyclodextrin-based ocular drug delivery systems: A comprehensive review
Q Wang, A Zhang, L Zhu, X Yang, G Fang… - Coordination Chemistry …, 2023 - Elsevier
… A summary of cyclodextrin (CD)-based ocular drug delivery systems based on formation of
… for ocular drug delivery and promote the clinical translation of CD-based ocular drug delivery …
… for ocular drug delivery and promote the clinical translation of CD-based ocular drug delivery …
Effect of cyclodextrins on topical drug delivery to the eye
T Loftsson, E Stefánsson - Drug development and industrial …, 1997 - Taylor & Francis
… and aqueous cyclodextrin eye drop formulations on the ocular … effect of cyclodextrin
complexation on bioavailability after ocular … of cyclodextrin to the aqueous cyclodextrin …
complexation on bioavailability after ocular … of cyclodextrin to the aqueous cyclodextrin …
Cyclodextrins and topical drug delivery to the anterior and posterior segments of the eye
T Loftsson, E Stefánsson - International journal of pharmaceutics, 2017 - Elsevier
… maintain high drug concentrations in … drug/cyclodextrin complex microparticles with a mean
diameter of 2–4 μm, dissolved drug/cyclodextrin complex nanoparticles and dissolved drug …
diameter of 2–4 μm, dissolved drug/cyclodextrin complex nanoparticles and dissolved drug …
Chitosan/sulfobutylether-β-cyclodextrin nanoparticles as a potential approach for ocular drug delivery
AA Mahmoud, GS El-Feky, R Kamel… - International journal of …, 2011 - Elsevier
… was to develop chitosan nanoparticles using sulfobutylether-β-cyclodextrin (SBE-β-CD)
as … as ocular drug delivery systems. Econazole nitrate (ECO) was chosen as model drug …
as … as ocular drug delivery systems. Econazole nitrate (ECO) was chosen as model drug …
Cyclodextrins in drug delivery
T Loftsson, P Jarho, M Másson… - … opinion on drug delivery, 2005 - Taylor & Francis
… increase aqueous solubility of poorly soluble drugs, and to increase their bioavailability and
… that cyclodextrins can be used to improve drug delivery from almost any type of drug formula…
… that cyclodextrins can be used to improve drug delivery from almost any type of drug formula…
Cyclodextrins for drug delivery
AL Laza-Knoerr, R Gref, P Couvreur - Journal of drug targeting, 2010 - Taylor & Francis
… This review reports on the recent developments of CDs in drug delivery using various routes
… directly to the ocular surface, after the passage of the mucin layer. Some examples are …
… directly to the ocular surface, after the passage of the mucin layer. Some examples are …
Biopharmaceutical considerations in topical ocular drug delivery
NM Davies - Clinical and experimental pharmacology and …, 2000 - Wiley Online Library
… Results thus far have been equivocal, with one report documenting an increased ocular
bioavailability for a solution of a cyclodextrin–drug complex compared with a suspension having …
bioavailability for a solution of a cyclodextrin–drug complex compared with a suspension having …
Water-soluble complex of curcumin with cyclodextrins: enhanced physical properties for ocular drug delivery
D Nabih Maria, SR Mishra, L Wang… - … Drug Delivery, 2017 - ingentaconnect.com
… Method: To achieve our goal, curcumin was complexed with β -cyclodextrin and
hydroxypropyl-βcyclodextrin in two molar ratios (1:1 and 1:2) using co-solvent, co-solvent with …
hydroxypropyl-βcyclodextrin in two molar ratios (1:1 and 1:2) using co-solvent, co-solvent with …
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