… used to determine if ODC activity is necessary for the normal … (with triiodothyronine) cardiac
hypertrophy. Male Sprague-… Cardiac hypertrophy was produced by daily subcutaneous …

… response of omithine decarboxylase that precedes cardiac hypertrophy or regression observed
days later. In this experimental model of rat cardiac hypertrophy produced by constriction …

… decarboxylase (ODC) in the heart. Induction of ODC is known to occur in response to agents
that induce cardiac hypertrophy… development of a hypertrophic phenotype. Transgenic mice …

… Arginase activity was below the limit of detection (0.1 … cardiac hypertrophy was induced
using our standard protocol of daily ISO injections (20 mg/kg, ip) for 10 days, arginase activity in …

… decarboxylase activity. Spermine synthase did not change significantly during the treatment
and spermidine synthase increased only slightly. Therefore, the accumulation of polyamines …

… from compensated to non-compensated cardiac hypertrophy where an increased expression
of … to ODC activity and expression. As a molecular marker for myocardial hypertrophy the …

… Daily subcutaneous administration of 200 mg/kg of DFMO reduced cardiac putrescine … ,
nor was normal cardiac growth affected. ISO-induced cardiac hypertrophy was accompanied by …

… Cardiac hypertrophy is also associated with a shift from fatty acids to glucose as the primary
… agents that induce cardiac hypertrophy is the upregulation of Ornithine decarboxylase (ODC)…

… increased ornithine decarboxylase activity plays a part in the maintenance of the normal
relatively hypertrophied state of the left ventricle. This is distinct from such increases in activity of …

… We have showed that AngII induced cardiac hypertrophy accompanied by upregulation of
… levels could inhibit AngIIinduced cardiac hypertrophy involving an increased level of cellular …