[HTML][HTML] Design, optimization and evaluation of glipizide solid self-nanoemulsifying drug delivery for enhanced solubility and dissolution

RN Dash, H Mohammed, T Humaira… - Saudi Pharmaceutical …, 2015 - Elsevier
… The saturation solubility (SS) of glipizide in optimized SNEDDS … ) of glipizide solubility as
compared to its aqueous solubility (0.033 … to an enhanced solubility and dissolution of glipizide. …

Design, optimization, and evaluation of ezetimibe solid supersaturatable self-nanoemulsifying drug delivery for enhanced solubility and dissolution

RN Dash, H Mohammed, T Humaira - Journal of Pharmaceutical …, 2016 - Springer
This study was intended to develop a solid supersaturatable self-nanoemulsifying drug-delivery
system (solid S-SNEDDS) to improve the solubility and dissolution of a poorly water-…

Analysis and optimization of drug solubility to improve pharmacokinetics

RK Thapa, HG Choi, JO Kim, CS Yong - Journal of Pharmaceutical …, 2017 - Springer
… their solubility in the … review, we will mainly deal with solubility aspects of drugs along with
its measurement methods. Moreover, the methods of solubility enhancement and optimization

Solubility Enhancement of Ebastine by Formulating Microemulsion Using D-Optimal Mixture Design: Optimization and Characterization

AR Barve, GR Kapileshwari, CEM DCruz… - ASSAY and Drug …, 2022 - liebertpub.com
… In practice, D-optimal mixture design optimization is done without using drug because the
amount of drug to be present in a formulation is constant and while optimization, the amount of …

Ketoprofen–FA Co-crystal: In Vitro and In Vivo Investigation for the Solubility Enhancement of Drug by Design of Expert

S Devi, A Kumar, A Kapoor, V Verma, S Yadav… - AAPS …, 2022 - Springer
… the fumaric acid forms the soluble complex with the drug and thereby increases the drug
wettability that leads to a better solubility and further heads towards better rate of drug release. …

[PDF][PDF] Formulation and evaluation of carvedilol solid dispersion tablets for solubility enhancement

R Arun Raj, J Harindran - Eur J Biomed Pharm Sci, 2017 - researchgate.net
soluble drug having short half-life of 2-8 hours. The aim of the present study is to enhance
… absorption and thereby improved bioavailability. Oral bioavailability of drugs depends on its …

Rationalized approach for formulation and optimization of ebastine microemulsion using design expert for solubility enhancement

J Mehetre, K Vimal, T Mehta, M Gohel… - Journal of Drug Delivery …, 2019 - jddtonline.info
… of design of experiment with goal of solubility enhancement thereby boosting bioavailability
due to site specificity as well reduces systemic side effects and hence will enhance the …

[HTML][HTML] Formulation and optimization of quinoa starch nanoparticles: Quality by design approach for solubility enhancement of piroxicam

M Bhatia, S Rohilla - Saudi Pharmaceutical Journal, 2020 - Elsevier
… In the present study piroxicam loaded starch nanoparticles were prepared to enhance the
solubility of piroxicam by nanoprecipitation technique. The preparation of nanoparticles was …

Computer-based formulation design and optimization using Hansen solubility parameters to enhance the delivery of ibuprofen through the skin

BM Jameel, A Huynh, A Chadha, S Pandey… - International Journal of …, 2019 - Elsevier
… However, emulgels have not been evaluated for … design) to designing emulgels for the
topical application of ibuprofen. The main goals of this study were to design and optimize

Canagliflozin loaded SMEDDS: formulation optimization for improved solubility, permeability and pharmacokinetic performance

D Singh, AK Tiwary, N Bedi - Journal of Pharmaceutical Investigation, 2019 - Springer
… is to systematically optimize and develop microemulsion preconcentrates to improve the
solubility and oral bioavailability profile of canagliflozin employing D-optimal mixture design. …