Studies on dissolution enhancement and mathematical modeling of drug release of a poorly water-soluble drug using water-soluble carriers

N Ahuja, OP Katare, B Singh - European Journal of Pharmaceutics and …, 2007 - Elsevier
… carriers was studied for dissolution enhancement of a poorly … All the solid dispersions showed
dissolution improvement vis-… Mathematical modeling of in vitro dissolution data indicated …

Dissolution rate enhancement of parabens in PEG solid dispersions and its influence on the release from hydrophilic matrix tablets

F Tajarobi, S Abrahmsén-Alami, A Larsson - Journal of pharmaceutical …, 2011 - Elsevier
… the actual release from other hydrophilic polymer matrices than … dissolution rate of an
analogous series of parabens in solid solutions of PEG altered the release from swellable matrices

[PDF][PDF] Enhancement of solubility and dissolution rate of trandolapril sustained release matrix tablets by liquisolid compact approach

A Butreddy, N Dudhipala - Asian Journal of Pharmaceutic• Oct …, 2015 - researchgate.net
dissolution studies of optimized SR LSC (F3) formulation had shown sustained drug release
… whereas LSC tablets showed 94.1±3.11% drug release in 120 min. DSC and XRD analysis …

Mesoporous silica formulation strategies for drug dissolution enhancement: a review

CA McCarthy, RJ Ahern, R Dontireddy… - Expert opinion on …, 2016 - Taylor & Francis
… Pore channel length and morphology are also significant for drug loading and release in
the silica matrix. Gao et al. compared bimodal mesoporous silica (BMM) which has short …

[HTML][HTML] Modulation of drug release from hydrophilic matrices

S Tiwari, A Rajabi-Siahboomi - Pharmaceutical Technology Europe, 2008 - pharmtech.com
dissolution rate; for example, it has been reported that the addition of HPC to HPMC matrices
caused further retardation to the release … layer of the resultant matrix, reducing the diffusion …

Modeling and comparison of release profiles: Effect of the dissolution method

S Cascone - European Journal of Pharmaceutical Sciences, 2017 - Elsevier
… of the dissolution method on the release profiles, in this work the dissolution data will be …
erosion of the matrix, which as soon as is consumed, it sudden releases the drug contained. …

Dissolution enhancement and formulation of rapid-release lornoxicam mini-tablets

HM Tawfeek, IY Saleem, M Roberts - Journal of pharmaceutical sciences, 2014 - Elsevier
dissolution of lornoxicam (LOR) and to produce mini-tablets with an optimised system to
provide a rapid-release … -ray diffraction, flowability and dissolution techniques. Mini-tablets were …

Mesoporous silica sub-micron spheres as drug dissolution enhancers: Influence of drug and matrix chemistry on functionality and stability

L Brigo, E Scomparin, M Galuppo, G Capurso… - Materials Science and …, 2016 - Elsevier
… The matrix composition influenced drug solution maximal concentration, … dissolution
enhancement generated by a mesoporous structure. This effect was found to depend on both matrix

Bio-dis and the paddle dissolution apparatuses applied to the release characterization of ketoprofen from hypromellose matrices

B Ramos Pezzini, H Gomes Ferraz - AAPS PharmSciTech, 2009 - Springer
… of dissolution medium pH on drug release. Furthermore, since direct compression had not
shown to be appropriate to obtain the matrices … impact of granulation on drug release process. …

Analysis of macromolecular changes and drug release from hydrophilic matrix systems

S Jamzad, L Tutunji, R Fassihi - International Journal of Pharmaceutics, 2005 - Elsevier
… This task was accomplished via combined evaluation of dissolution studies, texture analysis
of the matrix over time, front movement determination and erosion of the tablets containing …