… Dissolution medium used was simulated intestinal fluid (SIF, … to provide sink conditions
(solubility of glipizide in SIF was … separation of glipizide in dissolution samples of Glucotrol XL …

… Glipizide (100 mg) was dissolved in minimal quantity of methanol and volume was made
up to 100 mL with 0.1 M HCl solution. From this, 10 mL of the solution was withdrawn and …

… to dissolution media pH and hydrodynamics change, while the release of glipizide from BT
… the core, the solubility of glipizide was improved and the glipizide solution was formed. As …

… of the glipizide which tends to be soluble in pH 6.8 buffer. The consistency of the dissolution
results … 4 depicts effect of hydrodynamics on the release profile of Glucotrol XL (4a) and H4 …

… , level of soluble components in the coating, solubility of the … soluble drugs as poorly
water-soluble drugs cannot dissolve … dispersion with PXM 188 to increase solubility [11]. The aim …

… solubility study: In this study, solubility data was used as a basis for the development of
dissolution medium for glipizide… that the dissolution rate of glipizide increased with increase in …

… studies and in vitro dissolution study data indicated that … were suitable for improving the
solubility of glipizide. The same … of water solubility and in vitro dissolution rate of glipizide by …

… to enhance the solubility of Glipizide by solid dispersion method and to formulate a mouth
dissolving … The solubility of Glipizide enhanced with different ratios of CCS by the kneading …

… made an attempt to enhance solubility and dissolution of rofecoxib (RXB) by solid dispersion
(SD) technique using various hydrophilic excipients like polyethylene glycol 6000 (PEG …

… drug dissolution and bioavailability of poorly soluble glipizide was achieved successfully.
So solid dispersion is the promising technique for solubility enhancement of glipizide. Among …