Solubility and dissolution enhancement strategies: current understanding and recent trends
… solubility and dissolution phenomenon that hinders the judgment in selecting suitable strategy
for improving aqueous solubility and/or dissolution … with solubility and dissolution, (ii) their …
for improving aqueous solubility and/or dissolution … with solubility and dissolution, (ii) their …
In vitro and in vivo studies on the complexes of glipizide with water-soluble β-cyclodextrin–epichlorohydrin polymers
S Nie, S Zhang, W Pan, Y Liu - Drug Development and Industrial …, 2011 - Taylor & Francis
… conclude that the higher drug solubility, increased drug dissolution rate, and relative lower
K s magnitude of the complex were attributed to this enhancement in AUC value of glipizide. …
K s magnitude of the complex were attributed to this enhancement in AUC value of glipizide. …
A transdermal delivery system for glipizide
… glipizide is better absorbed from acidic medium; however, at very low pH levels, the solubility
of glipizide … C to enhance dissolution, then allowed to cool and kept in a refrigerator till use. …
of glipizide … C to enhance dissolution, then allowed to cool and kept in a refrigerator till use. …
[PDF][PDF] Formulation and evaluation of glipizide sustained release tablets
… of fresh dissolution medium. Samples were suitably diluted and assayed at 223 nm for glipizide
… -sustained release obtained with lactose is due its water soluble and hydrophilic nature …
… -sustained release obtained with lactose is due its water soluble and hydrophilic nature …
Formulation and Optimization of Controlled Porosity Osmotic Pump Tablet for Oral Administration of Glipizide
SA Payghan - Asian Journal of Pharmaceutics (AJP), 2016 - asiapharmaceutics.info
… the poorly soluble drug and the dissolution medium. Spray drying of GZ results into increased
surface area and due to this reason GZ released from SDs exhibited faster dissolution rate …
surface area and due to this reason GZ released from SDs exhibited faster dissolution rate …
[PDF][PDF] Formulation and Evaluation of sustained release matrix tablets of Glipizide
S Sandhan, K Sapra, J Mor - Indian Journal of Pharmaceutical and …, 2013 - academia.edu
… in the case of matrix tablets containing Glipizide β-CD complexes. … enhance the solubility
and dissolution rate of glipizide (ii) in the formulation of controlled release products of glipizide …
and dissolution rate of glipizide (ii) in the formulation of controlled release products of glipizide …
Strategies to improve dissolution and oral absorption of glimepiride tablets: solid dispersion versus micronization techniques
X Ning, J Sun, X Han, Y Wu, Z Yan… - Drug development and …, 2011 - Taylor & Francis
… enhancement of glimepiride solubility … enhanced solubility. In addition, these results
are in accordance with the well-established formation of soluble complexes between water-soluble …
are in accordance with the well-established formation of soluble complexes between water-soluble …
[PDF][PDF] DESIGN AND IN-VITRO EVALUATION OF INCLUSION COMPLEX OF WATER INSOLUBLE DRUG GLIPIZIDE
RA Khan, MM Iqbal, MA ur Rehman, A Khan - 2023 - wjpr.s3.ap-south-1.amazonaws.com
… increase the dissolution and bioavailability of poorly water-soluble drugs… solubility and
dissolution rate of Glipizide by solid dispersions (SDs) and investigate them for in vitro dissolution …
dissolution rate of Glipizide by solid dispersions (SDs) and investigate them for in vitro dissolution …
Compression-coated tablets of glipizide using hydroxypropylcellulose for zero-order release: In vitro and in vivo evaluation
H Huang, Z Wu, X Qi, H Zhang, Q Chen, J Xing… - International journal of …, 2013 - Elsevier
… for the better reproduction. Briefly, excess methanol was added to dissolve glipizide, while
… The solubility of glipizide in different pH solutions increased because of the manufacture of …
… The solubility of glipizide in different pH solutions increased because of the manufacture of …
[PDF][PDF] Development and evaluation of glipizide floating tablet
BK Nanjwade, SA Adichwal, KP Sutar - In vitro, 2012 - academia.edu
… Glipizide, a poorly soluble drug has been used as a model drug and an attempt has been
made to improve the solubility of … the available surface area so that wetting and dissolution can …
made to improve the solubility of … the available surface area so that wetting and dissolution can …