Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions
… These results show that the solubility and dissolution rate of SVS were not improved by
converting … form by CM, but that the solubility and dissolution of GPZ were somewhat improved. …
converting … form by CM, but that the solubility and dissolution of GPZ were somewhat improved. …
Improving glyburide solubility and dissolution by complexation with hydroxybutenyl-β-cyclodextrin
S Klein, MF Wempe, T Zoeller… - Journal of Pharmacy …, 2009 - academic.oup.com
… , with enhanced solubility and dissolution … solubility was also significantly improved in all
physiologically relevant test media. Subsequent dissolution experiments confirmed the solubility …
physiologically relevant test media. Subsequent dissolution experiments confirmed the solubility …
Delivery of glipizide from asymmetric membrane capsules using encapsulated excipients
AG Thombre, AR DeNoto, DC Gibbes - Journal of Controlled Release, 1999 - Elsevier
… deliver a poorly water soluble drug with a pH sensitive solubility such as glipizide. In order to
… The in vitro dissolution profiles of glipizide from asymmetric membrane capsules containing …
… The in vitro dissolution profiles of glipizide from asymmetric membrane capsules containing …
[PDF][PDF] Solubility enhancement of poorly hydrophilic drugs by using different newer techniques: A Review
HM Varshney, A Chatterjee - International journal of Therapeutic …, 2012 - npaa.in
… HME technique is utilized in the formulation development of poorly water-soluble
because of the enhanced dissolution properties, absorption and therapeutic efficacy.(16-17) …
because of the enhanced dissolution properties, absorption and therapeutic efficacy.(16-17) …
[PDF][PDF] Formulation development studies of bilayer tablet glipizide: A novel and evolutionary approach in the treatment of diabetes
G Bijank, D Rabindra, G Soumyadeep, C Manas… - Asian J. Pharm. Clin …, 2013 - Citeseer
… glipizide were characterized by FT-IR and in vitro dissolution … glipizide was evaluated using
USP-II paddle type dissolution … water solubility of this drug, its bioavailability is dissolution rate…
USP-II paddle type dissolution … water solubility of this drug, its bioavailability is dissolution rate…
[PDF][PDF] Formulation and evaluation of glipizide microemulsion
N Lavanya, C Aparna, B Umamahesh - Int J Pharm Pharm Sci, 2016 - academia.edu
… in increasing the dissolution of glipizide in GIT and … glipizide given orally are low [12]. The
novelty in the work is to develop a novel oral formulation of poorly water soluble drug, glipizide, …
novelty in the work is to develop a novel oral formulation of poorly water soluble drug, glipizide, …
[HTML][HTML] Formulation and evaluation of stabilized glipizide nanosuspension prepared by precipitation method
MS Raja, K Venkataramana - Evaluation, 2020 - rjptonline.org
… Glipizide is a BCS Class II drug which shows low solubility and high permeability 11-15 . The
nanosuspension approach is widely used to overcome the issues of solubility … dissolution …
nanosuspension approach is widely used to overcome the issues of solubility … dissolution …
[PDF][PDF] Formulation and Optimization of Controlled Porosity Osmotic Pump Tablet for Oral Administration of Glipizide
SC Patil, RM Chimkode, DA Bhagwat… - Asian Journal of …, 2016 - asiapharmaceutics.info
… the poorly soluble drug and the dissolution medium. Spray drying of GZ results into increased
surface area and due to this reason GZ released from SDs exhibited faster dissolution rate …
surface area and due to this reason GZ released from SDs exhibited faster dissolution rate …
A comparative study of top-down and bottom-up approaches for the preparation of nanosuspensions of glipizide
… highest solubility for glipizide (drug loading up to ~ 40 mg/5 ml) and was selected as the solvent
phase. Owing to poor solubility of glipizide … Glipizide was dissolved in acetone at definite …
phase. Owing to poor solubility of glipizide … Glipizide was dissolved in acetone at definite …
In vitro evaluation of novel sustained release microspheres of glipizide prepared by the emulsion solvent diffusion-evaporation method
P Phutane, V Lotlikar, A Ghule, S Sutar… - Journal of Young …, 2010 - Elsevier
… S100 along with ethyl cellulose was codissolved at room temperature in a solvent … Glipizide
was water insoluble, along with that Glipizide was practically insoluble in alcohol and soluble …
was water insoluble, along with that Glipizide was practically insoluble in alcohol and soluble …