Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions

K Löbmann, C Strachan, H Grohganz, T Rades… - European Journal of …, 2012 - Elsevier
… These results show that the solubility and dissolution rate of SVS were not improved by
converting … form by CM, but that the solubility and dissolution of GPZ were somewhat improved. …

Improving glyburide solubility and dissolution by complexation with hydroxybutenyl-β-cyclodextrin

S Klein, MF Wempe, T Zoeller… - Journal of Pharmacy …, 2009 - academic.oup.com
… , with enhanced solubility and dissolutionsolubility was also significantly improved in all
physiologically relevant test media. Subsequent dissolution experiments confirmed the solubility

Delivery of glipizide from asymmetric membrane capsules using encapsulated excipients

AG Thombre, AR DeNoto, DC Gibbes - Journal of Controlled Release, 1999 - Elsevier
… deliver a poorly water soluble drug with a pH sensitive solubility such as glipizide. In order to
… The in vitro dissolution profiles of glipizide from asymmetric membrane capsules containing …

[PDF][PDF] Solubility enhancement of poorly hydrophilic drugs by using different newer techniques: A Review

HM Varshney, A Chatterjee - International journal of Therapeutic …, 2012 - npaa.in
… HME technique is utilized in the formulation development of poorly water-soluble
because of the enhanced dissolution properties, absorption and therapeutic efficacy.(16-17) …

[PDF][PDF] Formulation development studies of bilayer tablet glipizide: A novel and evolutionary approach in the treatment of diabetes

G Bijank, D Rabindra, G Soumyadeep, C Manas… - Asian J. Pharm. Clin …, 2013 - Citeseer
glipizide were characterized by FT-IR and in vitro dissolutionglipizide was evaluated using
USP-II paddle type dissolution … water solubility of this drug, its bioavailability is dissolution rate…

[PDF][PDF] Formulation and evaluation of glipizide microemulsion

N Lavanya, C Aparna, B Umamahesh - Int J Pharm Pharm Sci, 2016 - academia.edu
… in increasing the dissolution of glipizide in GIT and … glipizide given orally are low [12]. The
novelty in the work is to develop a novel oral formulation of poorly water soluble drug, glipizide, …

[HTML][HTML] Formulation and evaluation of stabilized glipizide nanosuspension prepared by precipitation method

MS Raja, K Venkataramana - Evaluation, 2020 - rjptonline.org
Glipizide is a BCS Class II drug which shows low solubility and high permeability 11-15 . The
nanosuspension approach is widely used to overcome the issues of solubilitydissolution

[PDF][PDF] Formulation and Optimization of Controlled Porosity Osmotic Pump Tablet for Oral Administration of Glipizide

SC Patil, RM Chimkode, DA Bhagwat… - Asian Journal of …, 2016 - asiapharmaceutics.info
… the poorly soluble drug and the dissolution medium. Spray drying of GZ results into increased
surface area and due to this reason GZ released from SDs exhibited faster dissolution rate …

A comparative study of top-down and bottom-up approaches for the preparation of nanosuspensions of glipizide

KV Mahesh, SK Singh, M Gulati - Powder technology, 2014 - Elsevier
… highest solubility for glipizide (drug loading up to ~ 40 mg/5 ml) and was selected as the solvent
phase. Owing to poor solubility of glipizideGlipizide was dissolved in acetone at definite …

In vitro evaluation of novel sustained release microspheres of glipizide prepared by the emulsion solvent diffusion-evaporation method

P Phutane, V Lotlikar, A Ghule, S Sutar… - Journal of Young …, 2010 - Elsevier
… S100 along with ethyl cellulose was codissolved at room temperature in a solvent … Glipizide
was water insoluble, along with that Glipizide was practically insoluble in alcohol and soluble