Formation of bicalutamide nanodispersion for dissolution rate enhancement

C Li, C Li, Y Le, JF Chen - International journal of pharmaceutics, 2011 - Elsevier
Dissolution rate of bicalutamide nanodispersion was significantly faster than that of
commercial products. It was proposed that the enhanced dissolution rate of bicalutamide …

Preparation and characterization of nanocrystals for solubility and dissolution rate enhancement of nifedipine

J Hecq, M Deleers, D Fanara, H Vranckx… - International journal of …, 2005 - Elsevier
… shows the dissolution rate enhancement obtained with nano-sized systems as 95% of the
drug is dissolved following 60 min to 5% for the un-milled drug. Complete dissolution coming …

Microcrystals for dissolution rate enhancement of poorly water-soluble drugs

N Rasenack, H Hartenhauer, BW Müller - International journal of …, 2003 - Elsevier
… a poor dissolution rate. This study is intended to enhance the drug dissolution rate by
using … The dissolution rate is significantly enhanced (common drug: 4% after 20 min/microcrystals …

Dissolution Rate Enhancement by in Situ Micronization of Poorly Water-Soluble Drugs

N Rasenack, BW Müller - Pharmaceutical research, 2002 - Springer
… to enhance the dissolution rate of poorly water-soluble drugs. … Particle size, morphology,
dissolution rate, specific surface area… with markedly enhanced dissolution rate was obtained. …

Liquisolid technique for dissolution rate enhancement of a high dose water-insoluble drug (carbamazepine)

Y Javadzadeh, B Jafari-Navimipour… - International journal of …, 2007 - Elsevier
dissolution rate is often the rate-determining step in drug absorption. There are several methods
for enhancing dissolution rate … surface area, thus increasing dissolution rate of drug; (b) …

Solid dispersions, part I: recent evolutions and future opportunities in manufacturing methods for dissolution rate enhancement of poorly water-soluble drugs

DN Bikiaris - Expert opinion on drug delivery, 2011 - Taylor & Francis
dissolution enhancement of SDs is based on the fact that drugs in the nanoscale range, or in
amorphous phase, dissolve … the drug and the mechanism of dissolution rate enhancement. …

Liquisolid technology for dissolution rate enhancement or sustained release

AB Karmarkar, ID Gonjari… - Expert opinion on drug …, 2010 - Taylor & Francis
… Therefore, dissolution rate enhancement is the key aspect for absorption of these drugs.
Liquisolid technology is very efficient in the dissolution rate enhancement of these drugs. …

Solubility and dissolution rate enhancement of ibuprofen by co-milling with polymeric excipients

A Hussain, G Smith, KA Khan, NI Bukhari… - European Journal of …, 2018 - Elsevier
… to enhance the solubility and dissolution rate of ibuprofen. … are the enhancement of solubility
and dissolution rate of … the effect on solubility and dissolution rate of ibuprofen determined. …

Solid dispersions, part II: new strategies in manufacturing methods for dissolution rate enhancement of poorly water-soluble drugs

DN Bikiaris - Expert opinion on drug delivery, 2011 - Taylor & Francis
… Both dissolution kinetics and solubility are particle size … industry for dissolution rate
enhancement of such drugs. Among … been applied for the dissolution enhancement of poorly …

Mechanism of drug dissolution rate enhancement from β-cyclodextrin-drug systems

OI Corrigan, CT Stanley - Journal of Pharmacy and …, 1982 - academic.oup.com
… The observed dissolution rates … the enhanced drug dissolution rates, which are above those
predicted by the soluble complex model, are due to an extension of carrier phase dissolution