Effects of cyclodextrins on drug delivery through biological membranes

T Loftsson, SB Vogensen, ME Brewster… - Journal of …, 2007 - Elsevier
… Lipophilic cyclodextrins such as the methylated derivatives are thought to increase drug flux
by … The hydrophilic cyclodextrin family also modulate drug flux through membranes but via …

Cyclodextrins in drug delivery systems and their effects on biological barriers

Á Haimhoffer, Á Rusznyák, K Réti-Nagy… - Scientia …, 2019 - mdpi.com
… of larger drug delivery systems. On the other hand, they have numerous effects on cells or
… most important properties of cyclodextrins and cyclodextrin-based drug delivery systems are …

Cyclodextrins in drug delivery

T Loftsson, P Jarho, M Másson… - … opinion on drug delivery, 2005 - Taylor & Francis
… increase aqueous solubility of poorly soluble drugs, and to increase their bioavailability and
… that cyclodextrins can be used to improve drug delivery from almost any type of drug formula…

Cyclodextrins for drug delivery

AL Laza-Knoerr, R Gref, P Couvreur - Journal of drug targeting, 2010 - Taylor & Francis
… This review reports on the recent developments of CDs in drug delivery using various routes
… have demonstrated that the effects of CDs in rectal drug delivery depends on the type of …

Cyclodextrins in drug delivery systems

FJ Otero-Espinar, JJ Torres-Labandeira… - Journal of Drug Delivery …, 2010 - Elsevier
… , drug-conjugates) makes it possible to use cyclodextrins not only as drug solubilizers but also
as true delivery … of cyclodextrins mainly in solid and semi-solid drug delivery systems, from …

Effect of cyclodextrins on topical drug delivery to the eye

T Loftsson, E Stefánsson - Drug development and industrial …, 1997 - Taylor & Francis
… Branched cyclodextrins can be obtained by reacting cyclodextrin with glucose or maltose
in … cyclodextrin derivatives are formed by alkylation (eg, methyl- and ethyl-P-cyclodextrin) or …

Role of cyclodextrins in improving oral drug delivery

T Loftsson, ME Brewster, M Masson - American Journal of Drug Delivery, 2004 - Springer
… [47] The composition of the drug formulation, and the … cyclodextrins will enhance or
hamper drug delivery through a biologic membrane. Cyclodextrins will enhance drug delivery

Cyclodextrins in nasal drug delivery

F Merkus, JC Verhoef, E Marttin, SG Romeijn… - Advanced drug delivery …, 1999 - Elsevier
… The results of these studies seem not relevant for cyclodextrins used in nasal drug delivery,
because only small amounts are used and the residence time in the nose is very limited. …

Mechanisms by which cyclodextrins modify drug release from polymeric drug delivery systems

DC Bibby, NM Davies, IG Tucker - International journal of pharmaceutics, 2000 - Elsevier
… The mechanisms by which cyclodextrin/polymer formulations act to modify drug release …
cyclodextrins into polymeric drug delivery systems can influence the mechanisms by which drug

Cyclodextrins in ophthalmic drug delivery

T Loftssona, T Järvinen - Advanced drug delivery reviews, 1999 - Elsevier
… Recent studies have shown that cyclodextrins are useful … of ophthalmic drugs, and to
decrease drug irritation. However, … of cyclodextrins and administration of cyclodextrins via other …