Pharmaceutical applications of cyclodextrins: effects on drug permeation through biological membranes

T Loftsson, ME Brewster - Journal of Pharmacy and …, 2011 - academic.oup.com
… need to optimize the cyclodextrin amount and drug-to-cyclodextrin ratios. Drug formulations,
especially … There are numerous publications on the effects of CDs on drug delivery through …

Cyclodextrin superstructures for drug delivery

SS Braga - Journal of Drug Delivery Science and Technology, 2022 - Elsevier
… work shows that drug delivery systems based on cyclodextrin supramolecular constructs
offer a promising new platform for controlling the physico-chemical properties of drugs, as well …

[PDF][PDF] Cyclodextrins—a review on pharmaceutical application for drug delivery

R Agrawal, V Gupta - Int J Pharm Front Res, 2012 - academia.edu
… of drugs. This review article aims to asses the properties of cyclodextrin and their use in
drug delivery, … status and future scope for their usage in advanced drug delivery. Key words: …

Drugs-in-cyclodextrins-in liposomes: a novel concept in drug delivery

B McCormack, G Gregoriadis - International journal of pharmaceutics, 1994 - Elsevier
… Here we report on a novel concept (Gregoriadis and McCormack, 1993, 1994) in drug
delivery which, by taking advantage of certain properties of cyclodextrins and liposomes, …

Electrospinning of cyclodextrin functional nanofibers for drug delivery applications

F Topuz, T Uyar - Pharmaceutics, 2018 - mdpi.com
… embedded drug molecules. In this regard, cyclodextrins (CyD) are considered as ideal drug
carrier … with hydrophobic drugs and a hydrophilic exterior to increase the water-solubility of …

Investigation into the mechanism by which cyclodextrins influence transdermal drug delivery

CL Kear, J Yang, DA Godwin… - Drug development and …, 2008 - Taylor & Francis
… In this study, skin was first exposed to HPCD solutions as a “pretreatment,” thus allowing
the effect of the cyclodextrin on skin permeability to be assessed, rather than determining the …

Solubility of cyclodextrins and drug/cyclodextrin complexes

P Saokham, C Muankaew, P Jansook, T Loftsson - Molecules, 2018 - mdpi.com
… , increase its chemical and physical stability, and enhance drug delivery through biological
membranes. No covalent bonds are formed or broken during the complex formation and, in …

A vision for cyclodextrin nanoparticles in drug delivery systems and pharmaceutical applications

JR Lakkakula, RW Maçedo Krause - Nanomedicine, 2014 - Taylor & Francis
Cyclodextrinsdrug delivery. CDs, grafted or crosslinked with polymers, are now being
developed into 'smart' systems for efficient targeted drug delivery, especially for hydrophobic drugs

Cyclodextrins in drug delivery: an updated review

R Challa, A Ahuja, J Ali, RK Khar - Aaps Pharmscitech, 2005 - Springer
… findings and applications of cyclodextrins (CDs) and their derivatives in different areas of
drug delivery, particularly in protein and peptide drug delivery and gene delivery. The article …

Supersaturating drug delivery systems: effect of hydrophilic cyclodextrins and other excipients on the formation and stabilization of supersaturated drug solutions

ME Brewster, R Vandecruys, G Verreck… - Die Pharmazie-An …, 2008 - ingentaconnect.com
Supersaturating drug delivery systems (SDDS) utilize two important design elements in their
preparation including converting the drug of interest into a high energy state or other rapidly …