[PDF][PDF] Brief overview of various approaches to enhance drug solubility

ML Hart, DP Do, RA Ansari, SAA Rizvi - J. Dev. Drugs, 2013 - researchgate.net
… Poor solubility limits drug delivery and formulation development. Various techniques have
been developed to enhance solubility of poorly soluble drugs. Pharmaceuticals falling under …

Solubility enhancement and application of cyclodextrins in local drug delivery

DH Kim, SE Lee, YC Pyo, P Tran, JS Park - Journal of Pharmaceutical …, 2020 - Springer
… for drugs with poor aqueous solubility and low bioavailability. Because CDs can act as drug
… conjugate with many drugs, they have been applied in many drug delivery systems and can …

Self-Emulsifying Drug Delivery System: An Approach to Enhance Solubility.

R Tiwari, G Tiwari, AK Rai - Systematic Reviews in Pharmacy, 2010 - search.ebscohost.com
drug delivery systems (SEDDSs) have gained exposure for their ability to increase solubility
and bioavailability of poorly soluble drugs. … of the sparingly soluble drugs by rapid self-…

Self emulsifying drug delivery system for enhanced solubility and dissolution of glipizide

AG Agrawal, A Kumar, PS Gide - Colloids and Surfaces B: Biointerfaces, 2015 - Elsevier
drug delivery systems (SEDDS) of glipizide and to convert it into solid SEDDS (S-SEDDS)
using Syloid ® 244 FP as adsorbent. Solubility … -SEDDS compared with pure drug. The results …

Novel self-nanoemulsifying drug delivery system for enhanced solubility and dissolution of lutein

JH Yoo, S Shanmugam, P Thapa, ES Lee… - Archives of pharmacal …, 2010 - Springer
drug delivery system (SNEDDS) containing oil (Phosal 53 MCT), surfactant (Labrasol),
and cosurfactant (Transcutol-HP or Lutrol-E400) was prepared to enhance solubility and …

Solubility enhancers for oral drug delivery: can chemical structure manipulation be avoided?

CK Kim, JS Park - American Journal of Drug Delivery, 2004 - Springer
solubility properties.[2] The aim of this article is to review ways in which the solubility of these
highly lipophilic drugs can be enhanced, … that do not alter the chemical structure of the drug. …

[HTML][HTML] Design, optimization and evaluation of glipizide solid self-nanoemulsifying drug delivery for enhanced solubility and dissolution

RN Dash, H Mohammed, T Humaira… - Saudi Pharmaceutical …, 2015 - Elsevier
drug-delivery system (solid SNEDDS) has been explored to improve the solubility and …
area for drug solubilization leading to an enhanced solubility and dissolution of glipizide. …

Drug solubility: importance and enhancement techniques

KT Savjani, AK Gajjar, JK Savjani - … Scholarly Research Notices, 2012 - Wiley Online Library
… The improvement of drug solubility thereby its oral bio-… of drug development process
especially for oral-drug delivery … literature to enhance the solubility of poorly water-soluble drugs. …

Ultra fine super self-nanoemulsifying drug delivery system (SNEDDS) enhanced solubility and dissolution of indomethacin

F Shakeel, N Haq, M El-Badry, FK Alanazi… - Journal of molecular …, 2013 - Elsevier
solubility studies showed around 4573 fold enhancement in solubility in F1 formulation
compared to its aqueous solubilitydrug delivery of IND in order to enhance its solubility as well as …

Application of dendrimer–drug complexation in the enhancement of drug solubility and bioavailability

NK Jain, U Gupta - Expert opinion on drug metabolism & toxicology, 2008 - Taylor & Francis
… In addition dendrimers can be surface engineered to release the drug at desired site, that
is, as targeted drug delivery. This property along with the solubilisation behaviour could …