Effect of Xiaoyaosan on colon morphology and intestinal permeability in rats with chronic unpredictable mild stress

F Ding, J Wu, C Liu, Q Bian, W Qiu, Q Ma, X Li… - Frontiers in …, 2020 - frontiersin.org
gut-brain axis, this study explored the influence of Xiaoyaosan on the intestinal permeability
of … providing new insights for future studies on the antidepressant mechanism of Xiaoyaosan. …

[HTML][HTML] Xiaoyaosan slows cancer progression and ameliorates gut dysbiosis in mice with chronic restraint stress and colorectal cancer xenografts

Z Zhang, S Shao, Y Zhang, R Jia, X Hu, H Liu… - Biomedicine & …, 2020 - Elsevier
… Our present study aimed to investigate the effect of XYS on … In addition, the intestinal
permeability in the XYS group was … effects in reducing inflammation and intestinal permeability

[HTML][HTML] Xiaoyaosan improves depressive-like behavior in rats with chronic immobilization stress through modulation of the gut microbiota

HZ Zhu, YD Liang, QY Ma, WZ Hao, XJ Li… - Biomedicine & …, 2019 - Elsevier
… the effect of the decoction Xiaoyaosan (XYS) against depressive behavior through the
regulation of intestinal … to the reduction of intestinal permeability, intestinal inflammation and the …

Antidepressant effects of the traditional Chinese herbal formula Xiao-Yao-San and its bioactive ingredients

YT Wang, XL Wang, ZZ Wang, L Lei, D Hu, Y Zhang - Phytomedicine, 2023 - Elsevier
… Besides gut microbiota dysbiosis, XYS was found to inhibit the increase in gut permeability
and inflammatory cascades in mice with CRS and colorectal cancer xenografts (Zhang et al., …

Xiao-Yao-San reduces blood-brain barrier injury induced by chronic stress in vitro and vivo via glucocorticoid receptor-mediated upregulation of Occludin

S Yu, L Fu, J Lu, Z Wang, W Fu - Journal of ethnopharmacology, 2020 - Elsevier
… GCs induced BBB trauma models in vitro and in vivo to explore the effects of the traditional
medicine Xiao-Yao-San (XYS). In this research, we found CS could injure the BBB to change …

Research progress on classical traditional Chinese medicine formula xiaoyaosan in the treatment of depression

J Chen, C Lei, X Li, Q Wu, C Liu, Q Ma… - Frontiers in …, 2022 - frontiersin.org
effects of Xiaoyaosan are related to the effects of monoamine … , brain-gut axis, regulation of
intestinal microbiota, oxidative … and stress increase gut permeability and promote bacteria to …

Enhanced therapeutic effect on colitis with powder formulations of Painong San associated with the promotion of intestinal adhesion and absorption

J Li, X Rui, L Xu, Y Liu, Y Yang, D Yin - Journal of Ethnopharmacology, 2022 - Elsevier
… In this study, it was found that the better absorption effect of PNS is due to the combined
effect of drug particle retention and sustained release in the intestinal tract. However, the …

[PDF][PDF] Discussion on the mechanism of Xiaoyao Powder in the treatment of irritable bowel syndrome based on network pharmacology

QL Wu, Y Li, F Yang - Psychosom Med Res, 2022 - tmrjournals.com
effect on cell death and intestinal barrier dysfunction induced by quaternary ammonium salt
through Nrf2 signal transduction in intestinal … Chinese herbal medicine modified xiaoyao san

Ameliorative effect and mechanism of Si-Ni-San on chronic stress-induced diarrhea-irritable bowel syndrome in rats

HY Chen, J Liu, DZ Weng, L Yan, CS Pan… - Frontiers in …, 2022 - frontiersin.org
Effect of the SNS treatment on the expression of DβH and c-fos in locus coeruleus. (A) … MLC
and MLC expressions in the colon induced by CRS To study the effect of SNS on the release …

A preliminary study on the diversity of butyrate‐producing bacteria in response to the treatment of depression with Xiaoyaosan

LL Xiong, ML Mao, QL Shu - Letters in Applied Microbiology, 2022 - academic.oup.com
… by modulating the gut microbiota. However, the functional groups and mechanisms of action
in the … This study aimed to analyse with clone sequencing the changes in intestinal butyrate‐…