… In summary, we observed clear signs of relative energy deficiency, as evidenced by … -in-induced
hypernatremia and acute kidney injury. Our data therefore support publicized reports of …

… Another challenge lies in the vast energy demand of the kidneys, which increases … -deficient
mice with ischaemic AKI display lower kidney uric acid levels and milder kidney injury than …

… of energy metabolism and mitochondrial dysfunction are emerging as critical drivers of acute
kidney injury and … Deficiency in Pink1 and Park2 decreased mitophagy, worsened ischemic …

… -oxidant defense mechanisms, leading to cell and tissue injury. It is consistently accepted
that in CKD patients a deficiency in the antioxidant systems combines with an increase in pro-…

… to changes in nutrient availability and energy demand by maintaining mitochondrial … energy
to support renal function. We also explore how disease states, such as acute kidney injury (…

… for energy loss in cancer cachexia is the energy inefficient Cori cycle [43]. It is not known
whether futile cycles are responsible for the elevated resting energy expenditure in CKD. …

… A priori, we hypothesized that early PN would attenuate kidney injury. However, the original
study findings suggested that AKI incidence and renal recovery could be aggravated by …

… In acute kidney injury (AKI), mitochondrial dysfunction contributes to the physiopathology
of tissue injury, whereas mitochondrial biogenesis has an important role in the recovery of …

… are directly related to kidney disease, including increased resting energy expenditure (REE)…
-energy wasting (PEW) was proposed to denote concurrent losses in protein and energy …

… The recent research findings concerning syndromes of muscle wasting, malnutrition, and
inflammation in individuals with chronic kidney disease (CKD) or acute kidney injury (AKI) have …