… Enhancement of solubility, dissolution rate and bioavailability of drug is a very challenging
task in drug development, nearly 40% of the new chemical entities currently being discovered …

… The major advantage of this strategy is that, apart from enhancing solubility and dissolution
rate, these co-crystals are crystalline in nature with definite stoichiometry that improves its …

… screening have a very poor solubility [1]. It is well known that drug efficacy can be severely
limited by poor aqueous solubility, leading to low dissolution rate and thus result in low …

… API for enhanced solubility, stability, dissolution rate and bioavailability etc. Thermodynamic
and phase diagrams are a powerful and sensitive tool for selecting a useful technique and …

… , and bioavailability of poorly water soluble drugs include micronization, chemical … their low
solubility and dissolution rates. They require enhancement in solubility and dissolution rate in …

Poorly water-soluble drugs such as nifedipine (NIF) (∼20μg/ml) offer challenging problems
in drug formulation as poor solubility is generally associated to poor dissolution …

… the physical state of the drug to amorphous or partially amorphous state leads to a high
energy state and high disorder, resulting in enhanced solubility and faster dissolution. …

… bioavailability of active agents include; enhancing solubility and dissolution rate of poorly
water-soluble drugs and enhancing permeability of poorly water soluble drugs.The BCS is a …

… The objective of this study was to assess the contribution of surfactant-mediated solubility
and micellar diffusivity on the ability of surfactants to enhance drug dissolution. The effect of …

… has been recognized as an important element in drug development and thus increasing
the dissolution rate of poorly soluble drugs and enhancing their bioavailability is an important …