Mechanisms of resistance to chemotherapy in gastric cancer

JJG Marin, R Al-Abdulla, E Lozano… - Anti-Cancer Agents …, 2016 - ingentaconnect.com
… with a poorer prognosis and enhanced resistance to cisplatin and tyrosine kinase inhibitors.
… -5 in gastric cancer, the advances made in the prediction of the failure of chemotherapy, and …

[HTML][HTML] Molecular mechanisms of chemoresistance in gastric cancer

WJ Shi, JB Gao - World journal of gastrointestinal oncology, 2016 - ncbi.nlm.nih.gov
… The mechanisms of chemotherapy resistance in gastric cancer are complex and multifactorial.
A variety of factors have been demonstrated to be involved in chemoresistance, including …

Molecular mechanism of resistance to chemotherapy in gastric cancers, the role of autophagy

LV Spirina, AV Avgustinovich, SG Afanas' ev… - Current drug …, 2020 - ingentaconnect.com
… and converts cell phenotype toward malignant, contributing to chemoresistance and poor
prognosis of gastric cancer. The experimental data on the resistance of GC to cisplatin and 5-…

Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells

X Guo, N Ma, J Wang, J Song, X Bu, Y Cheng, K Sun… - BMC cancer, 2008 - Springer
… In this study, we found that constitutive overexpression of the MDR1 gene in drug-resistant
human gastric cancer SGC7901/VCR cells is dependent on phosphorylation of p38 and the …

Upregulation of THBS1 is Related to Immunity and Chemotherapy Resistance in Gastric Cancer

X Zhang, T Huang, Y Li, H Qiu - International journal of general …, 2021 - Taylor & Francis
… Clinically recommended chemotherapy regimens for gastric cancer include FLOT and
FOLFOX regimens, which can effectively prolong the overall survival of advanced GC. Citation34 …

New insights into the mechanisms of gastric cancer multidrug resistance and future perspectives

D Zhang, D Fan - Future Oncology, 2010 - Taylor & Francis
Chemotherapy is one of the major treatment options for advanced gastric cancer. The
efficacy of chemotherapy for gastric cancer is poor due to insensitivity and the development of …

CD44 expression denotes a subpopulation of gastric cancer cells in which Hedgehog signaling promotes chemotherapy resistance

C Yoon, DJ Park, B Schmidt, NJ Thomas, HJ Lee… - Clinical cancer …, 2014 - AACR
gastric CSC phenotypes, including chemotherapy resistance. We grew three different gastric
cancer cell … cells were highly resistant to 5-fluorouracil or cisplatin chemotherapy, and this …

Multidrug resistance in gastric cancer: recent research advances and ongoing therapeutic challenges

D Zhang, D Fan - Expert review of anticancer therapy, 2007 - Taylor & Francis
resistance of human gastric cancer. The absence of P-gp and MRP1 expression in some
gastric cancer … 20 years on gastric cancer chemotherapy and drug resistance appear to have an …

Silence of long noncoding RNA UCA1 inhibits malignant proliferation and chemotherapy resistance to adriamycin in gastric cancer

C Shang, Y Guo, J Zhang, B Huang - Cancer chemotherapy and …, 2016 - Springer
… might act as an oncogene in gastric cancer. However, little is … and chemotherapy resistance
in gastric cancer cells. In this … and chemotherapy resistance to adriamycin in gastric cancer

A review of research progress in multidrug-resistance mechanisms in gastric cancer

T Ruan, W Liu, K Tao, C Wu - OncoTargets and therapy, 2020 - Taylor & Francis
… However, the drug-resistance to the chemotherapy restricts its effect and … resistance in
gastric cancer. And we also want to find new approaches to counteract chemotherapy resistance