… of such loci with small effects on BP, opening a perspective on the genetic architecture of BP
that was unknown before. It is our hope that the knowledge of these and further loci will lead …

… More than 500 loci implicated in the regulation of BP have been revealed by genome-… BP
genetic loci to over 1000. Even with the large number of loci now associated to BP, the genetic …

… genes initially focused on genome-wide linkage studies that were successful in uncovering
genes for monogenic forms of high and low blood pressure … The key genes at each locus are …

… loci that influence blood pressure and cause genetic hypertension is a major challenge.
Several genetically … An unidentified genetic locus influencing a quantitative genetic trait such as …

… We therefore formed the Global Blood Pressure Genetics (Global BPgen) consortium and …
loci showing genome-wide significant association with systolic or diastolic blood pressure, …

… undertaken using sparse microsatellite marker sets, but we now know that these approaches
were underpowered to detect gene loci linked to essential hypertension or blood pressure. …

… As SHRSP animals show increases in blood pressure in response to … blood pressures
and blood pressures after twelve days of oral loading with NaCl (NaCl-loaded blood pressure) …

… The IGF-I gene locus was reported to be linked to systolic BP in a small population of
dizygotic twins and their parents [130] . The absence of the 192 base pair allele in the promoter …

… locus and blood pressures, we have studied mice carrying zero, one, two, three, or four
functional copies of the murine wild-type angiotensinogen gene (… The blood pressures of the one-…

… We report 4 novel loci associated with BP regulation, and 1 independent variant … locus.
This analysis highlights several candidate genes with variation that alter protein function or gene …