Improvement of water solubility and in vitro dissolution rate of gliclazide by complexation with β-cyclodextrin
Y Özkan, T Atay, N Di̇kmen, A Işimer… - Pharmaceutica Acta …, 2000 - Elsevier
… properties of gliclazide via complexation with β-CD. Furthermore, the dissolution rate profile
… According to our results from the dissolution rate studies, inclusion complexes prepared by …
… According to our results from the dissolution rate studies, inclusion complexes prepared by …
Comparison of the solubility and dissolution rate between gliclazide solid complex and its nanospheres
YK Lo, CJ Chen, TR Tsai, TM Cham - Drug development and …, 2007 - Taylor & Francis
… The solid complex of gliclazide and β-cyclodextrin … of gliclazide. In summary, the results
indicate that nanotechnology provides better effects in solubility and dissolution rate of gliclazide …
indicate that nanotechnology provides better effects in solubility and dissolution rate of gliclazide …
Cogrinding as an approach to enhance dissolution rate of a poorly water-soluble drug (gliclazide)
M Barzegar-Jalali, H Valizadeh, MRS Shadbad… - Powder Technology, 2010 - Elsevier
… gliclazide dissolution rate using PVP, Avicel and crospovidone. The fastest dissolution rates
… The solid state studies confirmed that cogrinding of gliclazide with a carrier can decrease …
… The solid state studies confirmed that cogrinding of gliclazide with a carrier can decrease …
Dissolution enhancement of gliclazide using in situ micronization by solvent change method
J Varshosaz, R Talari, SA Mostafavi, A Nokhodchi - Powder Technology, 2008 - Elsevier
… The low water-solubility of GL leads to a low dissolution rate and variable bioavailability.
The aim of this study was to enhance the dissolution rate of GL by the preparation of micron-…
The aim of this study was to enhance the dissolution rate of GL by the preparation of micron-…
Enhancement of dissolution rate of gliclazide using solid dispersions with polyethylene glycol 6000
… dissolution rate of gliclazide using its solid dispersions (SDs) with polyethylene glycol (PEG)
6000. The phase solubility behavior of gliclazide … The solubility of gliclazide increased with …
6000. The phase solubility behavior of gliclazide … The solubility of gliclazide increased with …
[PDF][PDF] Improvement of dissolution rate of gliclazide through sodium salt formation
D El-Sabawi, II Hamdan - Dissolution Technol, 2014 - researchgate.net
… solubility. Moreover, sodium gliclazide showed an enhancement in the dissolution rate in all
… The highest difference (60%) in dissolution rate between gliclazide and its sodium salt was …
… The highest difference (60%) in dissolution rate between gliclazide and its sodium salt was …
Solubility and dissolution enhancement of gliclazide by solid dispersion technique
CG More, PS Dabhade, NP Jain… - International Journal of …, 2015 - indianjournals.com
… Most NCE are poorly water soluble drugs, not well-absorbed after oral administration. Solid
… to enhance dissolution rate and solubility of poorly water soluble drug. Gliclazide is a second …
… to enhance dissolution rate and solubility of poorly water soluble drug. Gliclazide is a second …
[PDF][PDF] Dissolution enhancement of gliclazide using pH change approach in presence of twelve stabilizers with various physico-chemical properties
R Talari, A Nokhodchi, SA Mostafavi… - … of Pharmacy & …, 2009 - frontierspartnerships.org
… faster dissolution rate than untreated gliclazide particles and … solubility in alkaline medium.
Therefore, the aim of the investigation was to increase solubility/dissolution rate of gliclazide …
Therefore, the aim of the investigation was to increase solubility/dissolution rate of gliclazide …
[PDF][PDF] Enhancement of dissolution rate of gliclazide using solid dispersions: characterization and dissolution rate comparison
… permeability, the solubility and or dissolution rate of a drug … in the solubility and dissolution
rate of gliclazide by preparing solid … of poorly water soluble molecules like indomethacin (…
rate of gliclazide by preparing solid … of poorly water soluble molecules like indomethacin (…
Comparison of the solubility and dissolution rate of gliclazide-β-cyclodextrin inclusion complexes prepared by liquid/liquid extraction and neutralization
YK Lo, CP Hsu, TR Tsai, TM Cham - Journal of Food and Drug …, 2006 - jfda-online.com
… mode between GL and β-CD in the solid state using differ- … The dissolution rate and the
solubility of two solid complexes … to compare the dissolution rate and the solubility between these …
solubility of two solid complexes … to compare the dissolution rate and the solubility between these …
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