Investigation of the neuroprotective effects of crocin via antioxidant activities in HT22 cells and in mice with Alzheimer's disease

C Wang, X Cai, W Hu, Z Li, F Kong… - International …, 2019 - spandidos-publications.com
… In l‑glutamate‑damaged HT22 cells, 3‑h crocin pretreatment strongly enhanced the HT22
cell viability, reduced the apoptotic rate, mitigated mitochondrial dysfunction, suppressed …

[HTML][HTML] Magnesium-L-threonate exhibited a neuroprotective effect against oxidative stress damage in HT22 cells and Alzheimer's disease mouse model

Y Xiong, YT Ruan, J Zhao, YW Yang… - World journal of …, 2022 - ncbi.nlm.nih.gov
… APPswe/PS1dE9 (APP/PS1) mice were orally administered with MgT daily for 3 mo. … HT22
cells was determined via conducting cell counting kit-8 test and the cognition of APP/PS1 mice

… attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ1-42-induced Alzheimer's disease mice and glutamate-injured HT22 cells

S Yang, Z Xie, T Pei, Y Zeng, Q Xiong, H Wei, Y Wang… - Chinese Medicine, 2022 - Springer
… Based on the important role of Nrf2 in the pathogenesis of AD, this study investigated
whether salidroside could alleviate ferroptosis in HT22 cells and AD mice by regulating Nrf2. …

[HTML][HTML] α-Synuclein induced cell death in mouse hippocampal (HT22) cells is mediated by nitric oxide-dependent activation of caspase-3

A Adamczyk, A Kaźmierczak, GA Czapski… - FEBS letters, 2010 - Elsevier
cells (HT22), was designed to extend the previous results by showing the molecular pathway
of NO-mediated cell … ) and increase caspase-3 activity in HT22 cells, leading to poly(ADP-…

MST1 regulates neuronal cell death via JNK/Casp3 signaling pathway in HFD mouse brain and HT22 cells

M Khan, BPF Rutten, MO Kim - International journal of molecular sciences, 2019 - mdpi.com
… and amyloid pathology in HFD-fed mice and HT22 cells exposed to stress-inducing agents.
… Our result also showed that HFD-fed mice and HT22 cells treated with metabolic stress-…

Anti-Oxidative Stress Activity Is Essential for Amanita caesarea Mediated Neuroprotection on Glutamate-Induced Apoptotic HT22 Cells and an Alzheimer's Disease …

Z Li, X Chen, W Lu, S Zhang, X Guan, Z Li… - International journal of …, 2017 - mdpi.com
… and d-gal- and AlCl 3 -induced experimental AD mice were used to investigate the
activities of A. caesarea aqueous extracts (AC) on AD. Encouragingly, AC protected l-Glu-damaged …

Protective effects of caffeic acid and caffeic acid phenethyl ester against acrolein-induced neurotoxicity in HT22 mouse hippocampal cells

Y Huang, M Jin, R Pi, J Zhang, M Chen, Y Ouyang… - Neuroscience …, 2013 - Elsevier
… against acrolein-induced cell death, we … cell death in the murine hippocampal neuronal
cell line HT22. To accomplish this, first we investigated the toxicity of acrolein in HT22 cells. …

Effects of hypoxia on progranulin expression in HT22 mouse hippocampal cells

L Luo, L Lü, Y Lu, L Zhang, B Li… - Molecular …, 2014 - spandidos-publications.com
… -apoptotic and anti-inflammatory properties in focal cerebral ischemic mice (30). PGRN
expression is upregulated following spinal contusion in mice (9), but traumatic brain injury may …

Germinated brown rice attenuates cell death in vascular cognitive impaired mice and glutamate-induced toxicity in HT22 cells

EM Oo, K Ruamyod, L Khowawisetsut… - Journal of agricultural …, 2020 - ACS Publications
… memory deficits in mice with mild cerebral hypoperfusion using a mouse model of modified
bilateral common carotid artery occlusion (BCCAo) and glutamate-induced HT22 cell death. …

Effects of radiofrequency field exposure on glutamate-induced oxidative stress in mouse hippocampal HT22 cells

JY Kim, HJ Kim, N Kim, JH Kwon… - International Journal of …, 2017 - Taylor & Francis
… in HT22 cells. Glutamate augmented the subG1 fraction of cell cycle, annexin/propidium
iodide positive cell … followed by cell death and restored cell proliferation in HT22 cells. Finally, …