… focused on examining white matter pathology of the spine, the availability of fMRI offers a …
both the aging spinal cord and the brain in individuals with CSM [9]. Imaging the brain of CSM …

… in frontal and temporal cortex and in the Iimbic system of aging individuals. These changes
commence with loss of dendritic spines, are followed by changes in the size and shape of …

… As a context for changes in spines with aging, first we briefly review quantitative studies
of age-related changes in the morphology of neurons that possess dendritic spines. The …

… During the human lifespan, the spinal column is exposed to many continuously recurring …
Additionally the aging spine undergoes considerable changes in shape, particularly in …

… that aging is associated with alterations in synaptic dynamics. We find that the density of
spines … Rather than the expected spine loss with aging, we observed that the density of spines …

… Aging of the brain can manifest itself as a memory and cognitive decline, which has been …
of dendritic spines. Decreased number and maturity of spines in aged animals and humans, …

… We also discuss how aging processes and physiological changes in our body are reflected
… in the spinal cord motor circuitries. The complex, multifaceted connectivity of the spinal cord …

… of spine is of clinical significance. This paper reports the growth and degenerative pattern of
human spine … Whether it is genomics, study of human brain dynamics, analysis of biological …

… spine loss may probably underlie the first signs of cognitive decline in learning and memory
performance noted in normal aging. … Human brain is slow to reveal its secrets. The challenge …

… to the aging process was made on the human spinal cord. The … had no correlation with the
aging process. A significant correlation … to decrease according to the aging process, although …