… mechanisms involved in the regulation of human myometrial activity and the modulation of
these … of calcium homeostatic pathways to the control of human myometrial contractility during …

… A rise in intracellular calcium is the primary trigger for contractile activity in pregnant human
myometrium. It is hypothesized that key proteins involved in myometrial calcium homeostasis …

… that determine uterine contractility: the contractile apparatus; electrophysiology of the myocyte
including excitation-contraction coupling; and regulation of the sensitivity of the contractile …

… myometrium stems from a need to control uterine contractile activity in pregnancy. Signaling
pathways … transduction relating to myometrial Ca 2+ homeostasis have been identified and …

… regulating Ca2 + homeostasis. cAMP has inhibitory iffects on myometrial contractile activity,
… (Ca2 + J ,I with an emphasis on pathways affected by G-protein-coupled receptor signaling, …

… 3.2 Pathway to Contraction Figure 10.4 illustrates a schematic representing a uterine myocyte
and the pathways leading to contraction, and how they might be inhibited, for example to …

… Calcium homeostasis within the SR is important not only for the reliability of the release …
that they may target specific signal transduction pathways (eg transcription factors in the nucleus …

… calcium homeostasis through effects on membrane potential. … uterine contractile hormone
oxytocin stimulates myometrial … In rat and human myometrial membranes, oxytocin stimulated …

… conditions in adult rat and human myometrium (Wray, unpublished observation). Our …
human myometrial contractility during pregnancy and labour: Arc calcium homeostatic pathways …

… in our understanding of the physiology of uterine contractility of human labour. … myometrial
contractility. The ER also plays a major role in regulating cytoplasmic calcium homeostasis: …