[HTML][HTML] TNF-α modulation of intestinal tight junction permeability is mediated by NIK/IKK-α axis activation of the canonical NF-κB pathway

R Al-Sadi, S Guo, D Ye, M Rawat, TY Ma - The American journal of …, 2016 - Elsevier
… increase in intestinal tissue expression of MLCK and increase in mouse intestinal permeability
(… increase in mouse intestinal permeability was also regulated by NIK/NF-κB p50/p65 axis …

TNF-α-induced increase in intestinal epithelial tight junction permeability requires NF-κB activation

TY Ma, GK Iwamoto, NT Hoa, V Akotia… - American Journal …, 2004 - journals.physiology.org
… in intestinal TJ permeability could be a contributing factor of intestinal permeability defect in
CD. … involved in TNF-α modulation of intestinal epithelial TJ permeability by using an in vitro …

Tong-Xie-Yao-Fang improves intestinal permeability in diarrhoea-predominant irritable bowel syndrome rats by inhibiting the NF-κB and notch signalling pathways

Q Hou, Y Huang, Z Zhu, L Liao, X Chen, Q Han… - … and alternative medicine, 2019 - Springer
… degree of intestinal permeability [4]. According to our previous data, miR-144 regulates
intestinal permeability during IBS-D as an effective modulator of the intestinal tight junction …

QingBai decoction regulates intestinal permeability of dextran sulphate sodium‐induced colitis through the modulation of notch and NFκB signalling

JC Lin, JQ Wu, F Wang, FY Tang, J Sun, B Xu… - Cell …, 2019 - Wiley Online Library
intestinal epithelial cell apoptosis, but also affect the integrity of the mucosal barrier. The
damage of intestinal permeability … the intestinal permeability by inhibiting NF-κB signalling to …

[HTML][HTML] IL-1β-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-κB pathway

R Al-Sadi, D Ye, HM Said, TY Ma - The American journal of pathology, 2010 - Elsevier
… -induced alteration in intestinal permeability as a pathogenic factor of intestinal inflammation
has been supported by animal studies showing that the preservation of intestinal TJ barrier …

Mechanism of Interleukin-1β Induced-Increase in Mouse Intestinal Permeability In Vivo

R Al-Sadi, S Guo, K Dokladny, MA Smith… - Journal of Interferon & …, 2012 - liebertpub.com
intestinal permeability in vivo in an animal model system. Specifically, the IL-1β effect on
intestinal permeability … an isolated segment of mouse small intestine in vivo. Our data indicated …

[HTML][HTML] Lipopolysaccharide-induced increase in intestinal permeability is mediated by TAK-1 activation of IKK and MLCK/MYLK gene

M Nighot, M Rawat, R Al-Sadi, EF Castillo… - The American Journal of …, 2019 - Elsevier
… of NF-κB in LPS modulation of the intestinal TJ barrier. Previous studies have suggested that
both canonical and noncanonical NF-κB pathways play a regulatory role in intestinalNF-κB

… of prednisone inhibition of inflammation in Crohn's disease involve changes in intestinal permeability, mucosal TNFα production and nuclear factor kappa B …

GE Wild, KA Waschke, A Bitton… - Alimentary …, 2003 - Wiley Online Library
… of NF-κB mediated gene expression through blockade of NF-… effects of prednisone on
intestinal permeability, and whether … an inhibitory effect on mucosal TNFα and NF-κB expression. …

IL-1β causes an increase in intestinal epithelial tight junction permeability

RM Al-Sadi, TY Ma - The Journal of Immunology, 2007 - journals.aai.org
… vitro intestinalintestinal TJ permeability could be important in developing new therapeutic
approaches to induce retightening of the intestinal TJ barrier in various intestinal permeability

MicroRNA-29b-3p promotes intestinal permeability in IBS-D via targeting TRAF3 to regulate the NF-κB-MLCK signaling pathway

Y Wang, W Ke, J Gan, H Zhu, X Xie, G He, S Liu… - Plos one, 2023 - journals.plos.org
Intestinal hyperpermeability proved to play an important part in the pathogenesis of IBS-D
[5]. Maintenance of intestinal permeability relies on an intact intestinal barrier function. The …