Cyclodextrins in eye drop formulations

E Stefánsson, T Loftsson - Journal of inclusion phenomena and …, 2002 - Springer
… ophthalmology local drug administration is preferred and in the form of topically applied low
viscosity aqueous eye drop solutions. Fick’s First Law can be used to describe drug delivery

Bioactive glass as a drug delivery system of tetracycline and tetracycline associated with β-cyclodextrin

ZR Domingues, ME Cortés, TA Gomes, HF Diniz… - Biomaterials, 2004 - Elsevier
… implant is the local drug release system into the implant material as a carrier for a drug, such
as … Cyclodextrins are macrocyclic molecules with the ability to form complexes with specific …

Cyclodextrin microparticles for drug delivery to the posterior segment of the eye: aqueous dexamethasone eye drops

T Loftsson, D Hreinsdóttir… - Journal of pharmacy and …, 2007 - Wiley Online Library
… Previously we have investigated ophthalmic drug delivery after topical administration of
cyclodextrin-containing eye drop solutions (Loftsson & Stefánsson 1997, 2002). …

[PDF][PDF] Cyclodextrins: versatile carrier in drug formulations and delivery systems

S Ain, B Kumar, K Pathak - Int. J. Pharm. Chem. Biol. Sci, 2015 - academia.edu
… of applications of cyclodextrins (CDs) and their derivatives in different areas of drug delivery
and pharmaceuticalCyclodextrins were first described by Villiers in 1891. He described …

Porous silicon-cyclodextrin based polymer composites for drug delivery applications

J Hernandez-Montelongo, N Naveas, S Degoutin… - Carbohydrate …, 2014 - Elsevier
cyclodextrin-based polymers have been proven efficient materials for drug delivery, in this
work β-cyclodextrin–… tested as drug delivery platforms with two different model drugs, namely, …

The use of cyclodextrin inclusion complexes to improve anticancer drug profiles: A systematic review

SR Gandhi, JDSS Quintans, GR Gandhi… - … on Drug Delivery, 2020 - Taylor & Francis
Cyclodextrins (CDs) have been used extensively in inclusion complexes to improve the …
We reviewed in vivo experimental studies of drug molecules complexed in cyclodextrins to …

Self-assembled supramolecular hydrogels based on polymer–cyclodextrin inclusion complexes for drug delivery

J Li - NPG Asia Materials, 2010 - nature.com
… The supramolecular self-assembly of cyclodextrins (CDs) and polymers has led to the
development of novel supramolecular hydrogels for drug delivery applications. Many different …

Phase transition of a microemulsion upon addition of cyclodextrinapplications in drug delivery

SS Thakur, J Solloway, A Stikkelman… - Pharmaceutical …, 2018 - Taylor & Francis
… of cyclodextrin addition on … cyclodextrins. The prepared formulations underwent visual,
textural and microscopic characterization followed by the evaluation of their in vitro drug release

Development of a new delivery system consisting in “drug–in cyclodextrin–in nanostructured lipid carriers” for ketoprofen topical delivery

M Cirri, M Bragagni, N Mennini, P Mura - European Journal of …, 2012 - Elsevier
drug delivery system for ketoprofen topical administration based on a combined strategy
which exploits both cyclodextrin complexation, to enhance drug … improve drug delivery through …

Cross-linked hydroxypropyl-β-cyclodextrin and γ-cyclodextrin nanogels for drug delivery: Physicochemical and loading/release properties

MD Moya-Ortega, C Alvarez-Lorenzo… - Carbohydrate …, 2012 - Elsevier
… (γCD) and 2-hydroxypropyl-β-cyclodextrin (HPβCD) nanogels. These CDs were … to apply
the nanogels developed to topical delivery to the eye of drugs that require a sustained delivery, …