Polymeric micelles as drug delivery vehicles

Z Ahmad, A Shah, M Siddiq, HB Kraatz - Rsc Advances, 2014 - pubs.rsc.org
Drug delivery using micellar solutions of amphiphiles is an effective way of delivering drugs
to … Due to the hydrophobic environment of the core of micelles, water insoluble drugs can …

Block copolymer micelles as vehicles for drug delivery

K Kazunori, Y Masayuki, O Teruo, S Yasuhisa - Journal of controlled …, 1993 - Elsevier
… in the extravascular compartment subsequent to the extravasation of the micellar vehicle.
In summary, three major mechanisms involved in the polymeric micelle drug action are shown …

Polymeric micelles and alternative nanonized delivery vehicles for poorly soluble drugs

Y Lu, K Park - International journal of pharmaceutics, 2013 - Elsevier
… Despite increasing attention in polymer micelles as drug delivery vehicles for poorly soluble
drugs, so far much of the work has been conducted in a laboratory setting with very few in …

Micelles in anticancer drug delivery

D Le Garrec, M Ranger, JC Leroux - American Journal of Drug Delivery, 2004 - Springer
… nanodispersions are gaining in popularity,[18] dissolution of the active compound in the
delivery vehicle is still considered by many pharmaceutical companies as a prerequisite for …

Block copolymer micelles as delivery vehicles of hydrophobic drugs: micelle–cell interactions

R Savić, A Eisenberg, D Maysinger - Journal of drug targeting, 2006 - Taylor & Francis
… containers that simply solubilize hydrophobic drugs; cells internalize micelles. … micellar drug
delivery vehicles, we have to understand the fate of micelles and micelle-incorporated drugs

Block copolymer micelles as long-circulating drug vehicles

GS Kwon, K Kataoka - Advanced drug delivery reviews, 1995 - Elsevier
… of drugs have been solubilized by poloxamer micelles, as reviewed by Schmolka [41], the
concept that they serve as drug vehicles … , a non-polar, neuroleptic drug [42]. Haloperidol was …

Stabilized micelles as delivery vehicles for paclitaxel

K Yoncheva, P Calleja, M Agüeros, P Petrov… - International journal of …, 2012 - Elsevier
… Polymeric micelles present a great potential as drug delivery systems for compounds that …
The unique core–shell structure of micelles enables incorporation of poorly soluble drugs into …

Block copolymer micelles as long-circulating drug vehicles

GS Kwon, K Kataoka - Advanced drug delivery reviews, 2012 - Elsevier
… with other drug vehicles and with micelles formed from low molecular weight surfactants.
Micelle-forming, block copolymer-drug conjugates are described. Hydrophobic drugs, such as …

Evaluation of polyanion-coated biodegradable polymeric micelles as drug delivery vehicles

Y Ohya, S Takeda, Y Shibata, T Ouchi, A Kano… - Journal of controlled …, 2011 - Elsevier
… of them as drug delivery vehicles. To evaluate the fundamental properties of PLys-b-…
micelles coated with polyanionic HA (HA-coated micelles) as cyto-specific drug carriers, their drug

Drug delivery vehicles on a nano-engineering perspective

B Felice, MP Prabhakaran, AP Rodriguez… - Materials Science and …, 2014 - Elsevier
… new drug or encapsulate the old drug within a new drug delivery system such as the nDDS.
Design of a new drug … of drugs, and the effect is more visible in polymeric micelles. Polymeric …