[HTML][HTML] When less is more: reevaluating the role of intensive chemotherapy for older adults with acute myeloid leukemia in the modern era

NJ Short, H Kantarjian - Journal of Clinical Oncology, 2021 - ncbi.nlm.nih.gov
… in accurately assessing a patient's fitness for intensive chemotherapy (reviewed in detail by
intensive chemotherapy are almost universally based on retrospective analyses from an era

Clinical effectiveness of itraconazole as antifungal prophylaxis in AML patients undergoing intensive chemotherapy in the modern era

CL Keighley, P Manii, SR Larsen, S van Hal - European Journal of Clinical …, 2017 - Springer
Antifungal prophylaxis regimens vary between centres, informed by local epidemiology and
antifungal stewardship practices. The advantages of itraconazole over posaconazole …

Cardioprotection in the modern era of cancer chemotherapy

A Godishala, S Yang, A Asnani - Cardiology in review, 2018 - journals.lww.com
… to intensive ChemOtherapy for the treatment of Malignant hEmopathies), which showed a
lower incidence of the combined endpoint of death or heart failure in the enalapril/carvedilol …

Association of chemotherapy for solid tumors with development of therapy-related myelodysplastic syndrome or acute myeloid leukemia in the modern era

LM Morton, GM Dores, SJ Schonfeld, MS Linet… - JAMA …, 2019 - jamanetwork.com
… SEER are elevated in the modern treatment era following chemotherapy for liver, pancreas,
… /AML risks persist in the modern era following cytotoxic chemotherapy for female breast, soft …

Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome: comparison with historical experience

HM Kantarjian, S O'Brien, X Huang… - … Journal of the …, 2007 - Wiley Online Library
intensive chemotherapy (Fig. 1) and in a multivariate analysis using a larger historic control
group that received intensive chemotherapy in the modern era (hazard ratio for decitabine vs …

Induction therapy in the modern era of combined-modality therapy for locally advanced head and neck cancer

M Posner, JB Vermorken - Seminars in oncology, 2008 - Elsevier
… Thus, there was a 37% rate of local/regional failure when TPF induction chemotherapy was
followed by maximal intensive radiotherapy, suggesting that perhaps CRT in this setting may …

Optimizing therapy in the modern age: differences in length of maintenance therapy in acute lymphoblastic leukemia

DT Teachey, SP Hunger, ML Loh - Blood, The Journal of the …, 2021 - ashpublications.org
… disadvantage with modern intensive chemotherapy backbones. … by data in an era with
less-intensive early therapy, which was … With modern intensive risk-stratified therapy, there is no …

Combined cytotoxic chemotherapy and immunotherapy of cancer: modern times

C Bailly, X Thuru, B Quesnel - NAR cancer, 2020 - academic.oup.com
… A case of reversal of resistance to chemotherapy following … of optimizing chemotherapy
in the era of immunotherapy. … who are not eligible for intensive chemotherapy (38). These …

New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management

…, Intensive Care in Hematological and Oncological … - Critical Care, 2017 - Springer
… Antineoplastic chemotherapy classically targets various steps of cell proliferation, such as
DNA formation and function or the … These bespoke MABs initiated a new era of cancer drugs …

International Prognostic Score in advanced-stage Hodgkin's lymphoma: altered utility in the modern era

AA Moccia, J Donaldson, M Chhanabhai… - Journal of clinical …, 2012 - ascopubs.org
… In advanced-stage disease, multiagent chemotherapy … More recently, dose-intensive
chemotherapy regimens have … risk to be considered for more intensive therapy, and may also be …