… Potential models for explaining the observed associations of mosaic loss of Y chromosome
(… ” hypothesis of mosaic LOY (Forsberg 2017). This hypothesis describes that the mosaic LOY …

… X and Y chromosomes (156 Mb vs. 57 Mb). In addition, the human Y chromosome is enriched
… formation of isodicentric chromosomes and resultant chromosomal missegregation during …

… The known risk factors of mosaic LOY including age, genetic variants, ChrY … mosaic LOY
occurs and why ChrY is prone to lose. We believe it is importantly and timely to extend mosaic …

… of a Y chromosome provides a selective growth advantage in these cells; we hypothesize
that this could be due to the loss of a putative Y-linked cell-growth suppressor gene; loss of a Y-…

… For more than four decades, it has been noted that a fraction of healthy men lose all or some
portion of the Y chromosome over the course of their lifetime 1 . Moreover, several studies …

… Furthermore, variation on chromosome Y has been … Our results support the notion that
human chromosome Y is … elderly males frequently lose chromosome Y in normal hematopoietic …

… the Y chromosome for differential outcomes to cancer therapeutics. This review provides an
overview of the human Y chromosome … of the human Y chromosome is a mosaic of discrete …

… mosaic karyotype consisting of a 45,X cell line and a second cell line containing a normal or
an abnormal Y chromosome … such a mosaic karyotype for Y chromosome material loss and …

… human genetics and genomics. Until recently, it was believed that the function of human Y
chromosome … the association of mosaic aneuploidy of the Y chromosome in somatic cells with …

… had retained the ancestral autosome's gene content whereas the Y chromosome had lost
all … understanding of the human Y chromosome as a profoundly degenerate X chromosome. …