Developmental origin of smooth muscle cells in the descending aorta in mice

P Wasteson, BR Johansson, T Jukkola, S Breuer… - 2008 - journals.biologists.com
Aortic smooth muscle cells (SMCs) have been proposed to … aorta, and that SMCs later
migrate to the dorsal side. In this study, we investigate the origin of SMCs in the descending aorta

A simple method of isolating mouse aortic endothelial cells

M Kobayashi, K Inoue, E Warabi, T Minami… - … of atherosclerosis and …, 2005 - jstage.jst.go.jp
… of endothelial cells (EC) and smooth muscle cells (SMC) are very important. The mouse
is a critical model for research, however, the isolation of primary EC from murine aorta is …

Transdifferentiation of mouse aortic smooth muscle cells to a macrophage-like state after cholesterol loading

JX Rong, M Shapiro, E Trogan… - Proceedings of the …, 2003 - National Acad Sciences
… In summary, we have characterized the phenotypic changes associated with mouse aortic
SMC foam-cell formation at the protein and molecular level. These cells became macrophage-…

Aging, oxidative responses, and proliferative capacity in cultured mouse aortic smooth muscle cells

SK Moon, LJ Thompson… - American Journal …, 2001 - journals.physiology.org
… of vascular smooth muscle cells is … muscle cells (SMC) derived from the aortas of young (4
mo old) and aged (16 mo old) mice to understand the phenotypic modulation of these cells as …

Hemodynamic Shear Stress via ROS Modulates PCSK9 Expression in Human Vascular Endothelial and Smooth Muscle Cells and Along the Mouse Aorta

Z Ding, S Liu, X Wang, X Deng, Y Fan… - Antioxidants & redox …, 2015 - liebertpub.com
… Results: Using a parallel-plate flow chamber, we observed that PCSK9 expression in
vascular smooth muscle cells (SMCs) and endothelial cells (ECs) reached maximal value at low …

Vascular smooth muscle cell isolation and culture from mouse aorta

CS Kwartler, P Zhou, SQ Kuang, XY Duan, L Gong… - Bio …, 2016 - bio-protocol.org
cells may be usable beyond passage 6 but we recommend assessing the smooth muscle
cell phenotype of higher passage cells … by expression of smooth muscle myosin heavy chain, …

Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizer-like cells on combined tumor necrosis factor receptor-1/lymphotoxin β-receptor NF-κB …

K Lötzer, S Döpping, S Connert… - … , and vascular biology, 2010 - Am Heart Assoc
… Here, we show that mouse aorta SMC stimulated with TNF/α-LTβR differentiate into a
phenotype that strikingly resembles LTO. The LTO phenotype resulted from cross-talk of the …

Smooth muscle cell to elastic lamina connections in developing mouse aorta. Role in aortic medial organization.

EC Davis - Laboratory investigation; a journal of technical methods …, 1993 - europepmc.org
… The ultrastructural development and organization of connections between smooth muscle
cells and elastic laminae in the mouse aortic media were studied by light and electron …

Vasodilator efficacy of nitric oxide depends on mechanisms of intracellular calcium mobilization in mouse aortic smooth muscle cells

CE Van Hove, C Van der Donckt… - British journal of …, 2009 - Wiley Online Library
… Furthermore, it is important to note that relaxation by ACh in the mouse aorta was absent with
NOS inhibition, thus confirming that ACh-induced relaxation is exclusively mediated by NO, …

Immunostaining of macrophages, endothelial cells, and smooth muscle cells in the atherosclerotic mouse aorta

P Menon, EA Fisher - Methods in Mouse Atherosclerosis, 2015 - Springer
… macrophages, ECs and SMCs in mouse aortic atherosclerotic plaques using cell type-specific
markers. In … Here we outline the protocol for CD68 staining of frozen mouse aortic sections. …