Ornithine decarboxylase in cardiac hypertrophy in the rat
S Matsushita, RK Sogani, MS Raben - Circulation Research, 1972 - Am Heart Assoc
… is influenced at the stage of transcription by mechanical stress on the myocardium and
that polyamines might have a regulatory role in cardiac hypertrophy and regression. …
that polyamines might have a regulatory role in cardiac hypertrophy and regression. …
Overexpression of ornithine decarboxylase decreases ventricular systolic function during induction of cardiac hypertrophy
E Giordano, RA Hillary, TC Vary, AE Pegg, AD Sumner… - Amino Acids, 2012 - Springer
… However, failure to limit myocardial hypertrophy can itself reduce cardiac output and lead
to … Ornithine decarboxylase (ODC), the first and potentially rate-limiting enzyme of the …
to … Ornithine decarboxylase (ODC), the first and potentially rate-limiting enzyme of the …
Ornithine decarboxylase activity in the isolated perfused rat heart
P Antony, K Gibson, P Harris - Journal of Molecular and Cellular Cardiology, 1976 - Elsevier
… Isoprenaline, growth hormone, Ts and dibutyryl CAMP had no effect on myocardial ornithine
decarboxylase activity when added to the assay mixture in concentrations from 10-g to IO-3 …
decarboxylase activity when added to the assay mixture in concentrations from 10-g to IO-3 …
Role of ornithine decarboxylase in cardiac growth and hypertrophy
J Bartolome, J Huguenard, TA Slotkin - Science, 1980 - science.org
Inhibition of cardiac ornithine decarboxylase (ODC) by α-difluoromethylornithine (DFMO)
did not prevent normal cardiac growth in mature rats but attenuated isoproterenol-induced …
did not prevent normal cardiac growth in mature rats but attenuated isoproterenol-induced …
[HTML][HTML] Evidence that AMP-activated protein kinase can negatively modulate ornithine decarboxylase activity in cardiac myoblasts
CL Passariello, D Gottardi, S Cetrullo, M Zini… - … et Biophysica Acta (BBA …, 2012 - Elsevier
… A characteristic event in response to agents that induce cardiac hypertrophy is the upregulation
of Ornithine decarboxylase (ODC), the key enzyme in the biosynthesis of polyamines. …
of Ornithine decarboxylase (ODC), the key enzyme in the biosynthesis of polyamines. …
Central role for ornithine decarboxylase in β-adrenoceptor mediated hypertrophy
KD Schlüter, K Frischkopf, M Flesch… - Cardiovascular …, 2000 - academic.oup.com
… Therefore, elevation of total RNA is a key factor in myocardial … Ornithine decarboxylase
(ODC) represents the rate limiting … to the situation of the myocardium in vivo at the transition from …
(ODC) represents the rate limiting … to the situation of the myocardium in vivo at the transition from …
Targeted overexpression of ornithine decarboxylase enhances β-adrenergic agonist-induced cardiac hypertrophy
LM SHANTZ, DJ FEITH, AE PEGG - Biochemical Journal, 2001 - portlandpress.com
… the consequences of constitutive overexpression of ornithine decarboxylase (ODC) in the
heart… Despite these significant alterations in polyamines, myocardial hypertrophy, as measured …
heart… Despite these significant alterations in polyamines, myocardial hypertrophy, as measured …
Isoprenaline induced changes in ornithine decarboxylase activity and polyamine content in regions of the rat heart
UR TIPNIS, K FRASIER-SCOTT… - Cardiovascular …, 1989 - academic.oup.com
… in ornithine decarboxylase specific activity … ornithine decarboxylase activity was found in
the septum. Propranolol inhibited the isoprenaline stimulated ornithine decarboxylase activity in …
the septum. Propranolol inhibited the isoprenaline stimulated ornithine decarboxylase activity in …
Downregulation of the ornithine decarboxylase/polyamine system inhibits angiotensin-induced hypertrophy of cardiomyocytes through the NO/cGMP-dependent …
Y Lin, JC Liu, XJ Zhang, GW Li, LN Wang… - Cellular Physiology and …, 2010 - karger.com
… , Nawrath H, Wolfsgruber W, Kühbandner S, Werner C, Hofmann F, Feil R: cGMP-dependent
protein kinase I mediates the negative inotropic effect of cGMP in the murine myocardium. …
protein kinase I mediates the negative inotropic effect of cGMP in the murine myocardium. …
The effect of isoprenaline and propranolol on rat myocardial ornithine decarboxylase
JW WARNICA, P ANTONY, K GIBSON… - Cardiovascular …, 1975 - academic.oup.com
… in rats caused an increase in myocardial ornithine decarboxylase activity which reached a …
dl-propranolol had no effect on myocardial ornithine decarboxylase activity. The injection of dl-…
dl-propranolol had no effect on myocardial ornithine decarboxylase activity. The injection of dl-…
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