Hippocampal neuronal ferroptosis involved in cognitive dysfunction in rats with sepsis-related encephalopathy through the Nrf2/GPX4 signaling pathway

P Yao, Y Chen, Y Li, Y Zhang, H Qi… - … wei zhong bing ji jiu yi …, 2019 - europepmc.org
… reduced, neuronneurons were obviously damaged and ferroptosis was increased. Def
pretreatment could significantly reduce iron deposition and ferroptosis in hippocampal neurons

[HTML][HTML] Role and mechanism of ferroptosis in neurological diseases

M Ou, Y Jiang, Y Ji, Q Zhou, Z Du, H Zhu, Z Zhou - Molecular Metabolism, 2022 - Elsevier
… -1 could reduce the neuronal degeneration induced by ferroptosis to improve the motor and
… found as the ferroptosis inhibitor, which inhibit neuronal Fth-mediated ferroptosis of TBI [118]…

The calcium–iron connection in ferroptosis-mediated neuronal death

S Gleitze, A Paula-Lima, MT Núñez… - Free Radical Biology and …, 2021 - Elsevier
… is likely to disturb Ca 2+ homeostasis and signaling, facilitating ferroptotic neuronal death. …
and ferroptosis in neuronal function, emphasizing the possible involvement of Ca 2+ signaling

Ferroptosis and its role in diverse brain diseases

A Weiland, Y Wang, W Wu, X Lan, X Han, Q Li… - Molecular …, 2019 - Springer
… However, solid data have shown the presence of neuronal ferroptosis after ICH in vitro
and in vivo [35, 50, 98]. In 2014, we found that (−)-epicatechin, a brain-permeable flavanol, …

Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ1-42-induced Alzheimer's disease mice and glutamate-injured HT22 …

S Yang, Z Xie, T Pei, Y Zeng, Q Xiong, H Wei, Y Wang… - Chinese Medicine, 2022 - Springer
… role by alleviating neuronal ferroptosis in Aβ 1−42 -induced AD mice and Glu-injured
HT22 cells, and its mechanism is related to activation of the Nrf2/HO1 signaling pathway. …

Combined exposure of alumina nanoparticles and chronic stress exacerbates hippocampal neuronal ferroptosis via activating IFN-γ/ASK1/JNK signaling pathway in …

H Zhang, W Jiao, H Cui, Q Sun, H Fan - Journal of Hazardous Materials, 2021 - Elsevier
neuronal ferroptosis via IFN-γ/ASK1/JNK signaling pathway … exposures induce hippocampal
neuronal ferroptosis. The second … stress on hippocampal neuronal ferroptosis and cognitive …

Lipoxin A4 protects primary spinal cord neurons from Erastin‐induced ferroptosis by activating the Akt/Nrf2/HO‐1 signaling pathway

N Wei, T Lu, L Yang, Y Dong, X Liu - FEBS open bio, 2021 - Wiley Online Library
ferroptosis of primary spinal cord neurons by activating the Akt/Nrf2/HO-1 signaling pathway.
… of action of LXA4 in ferroptosis of primary spinal cord neurons and indicates that LXA4 may …

Dihydroorotate dehydrogenase regulates ferroptosis in neurons after spinal cord injury via the P53‐ALOX15 signaling pathway

D Li, X Lu, G Xu, S Liu, Z Gong, F Lu… - CNS Neuroscience …, 2023 - Wiley Online Library
… In this study, the effect of DHODH on neuronal ferroptosis was observed in vivo and in vitro
… performed to assess ferroptosis and explore the possible mechanisms in vivo and in vitro. …

Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons

Y Zhang, BY Fan, YL Pang, WY Shen… - Neural regeneration …, 2020 - journals.lww.com
… Therefore, we studied the mechanisms of ferroptosis using primary cortical neurons from …
-induced ferroptosis. Only deferoxamine protected the primary cortical neurons from ferroptosis

Ferroptosis contributes to hypoxic–ischemic brain injury in neonatal rats: Role of the SIRT1/Nrf2/GPx4 signaling pathway

C Li, Z Wu, H Xue, Q Gao, Y Zhang… - CNS neuroscience & …, 2022 - Wiley Online Library
… of ferroptosis in HIBI and the underlying signaling pathways. … /GPx4 signaling was involved
in HIBI-induced ferroptosis; and … effect by inhibiting neuronal ferroptosis, highlighting the latter …